Anti-allergy relieving composition and application thereof

Abstract

The invention relates to an anti-allergy relieving composition and application thereof. The anti-allergy relieving composition is prepared from the following components: a first anti-allergy composition, a second anti-allergy composition and an anti-allergy peptide composition, wherein active components of the first anti-allergy composition comprise 4-tert-butylcyclohexanol and hydroxyphenyl propionamide benzoic acid; active components of the second anti-allergy composition comprise radix stephaniae tetrandrae extract, potassium lactate, phenoxyethanol and dipotassium glycyrrhizinate; active components of the anti-allergy peptide composition comprise palmitoyl tripeptide-8 and acetyl tetrapeptide-15. After the anti-allergy relieving composition provided by the invention is evaluated through a macrophage nitric oxide inflammatory release model, the inhibition rate on the nitric oxide is 38.62 percent and the inhibition rate on histamine is 41.92 percent.

Description

technical field [0001] The invention relates to the technical field of skin care products, in particular to an anti-allergy soothing composition and its application. Background technique [0002] Allergic disease (also known as allergic disease) is not just a common disease, but has become a worldwide epidemic. In fact, an epidemiological survey of 1.2 billion people in 30 countries revealed that 250 million people (22%) suffer from allergic diseases. This is the survey data released by the World Allergy Organization (WAO), so July 8th is designated as World Allergic Disease Day every year. [0003] Mainly focus on food allergy, insect allergy, plant allergy, cosmetic allergy, photoallergy caused by ultraviolet rays, which cause skin itching, redness, fever, tingling, and tissue damage. [0004] The etiology of allergic diseases has not yet been definitively concluded, but the main reason for the accelerated increase in the incidence of the disease is the gradual deteriora...

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Problems solved by technology

[0008] Second-generation antihistamines: commonly used are cetirizine, loratadine, mizolastine, ebastine, etc., with few adverse reactions, but almost no obvious anticholinergic and sedative effects

However, it has recently been found that astemizole (Astemizole) and terfenadine (Mitel) may cause rare, severe cardiotoxicity, which can cause fatal arrhythmia; when combined with conazole and erythromycin, the above Adverse reactions

[0009] Third-generation antihistamines: such as desloratadine, fexofenadine, etc., have milder adverse reactions, and will not cause cardiotoxicity when used with erythromycin and ketoconazole, but there may also be potential unknown risks

[0010] There are also plant-based anti-allergic components on the market, but there are relatively few effective additives, mainly concentrated in chamomile, licorice, purslane, rhodiola, and more concentrated on skin repair and maintenance. The added amount and the most There are few studies on the optimal combination

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