6 results about "Terfenadine" patented technology

1. The name of the design product: poster (terfenadine granules 1). 2. The use of the design product: for poster. 3. The design points of the design product: in the combination of shape and pattern. 4. The picture or photo that best indicates the design points: front view. 5. The design product is a flat product, and the rear view, left view, right view, top view and bottom view are omitted.

This invention relates to the field of peptide preparation technology, specifically to a preparation process for terfenadine. The terfenadine preparation process includes the following steps: (1) using resin as a solid-phase carrier, Boc-Pip(Fmoc)-OH is loaded onto the resin to obtain Boc-Pip(Fmoc)-resin; (2) under the action of a condensing agent, Fmoc-D-Lys(Boc)-OH and Boc-D-Phe-D-Phe-D-Leu-OH are sequentially coupled onto the Boc-Pip(Fmoc)-resin to obtain terfenadine peptide resin; (3) the terfenadine peptide resin is lysed using a lysis buffer, then concentrated, precipitated, and dried to obtain crude terfenadine. This invention's preparation process can effectively improve product purity while ensuring large-scale industrial production, and the steps are simple with a short reaction cycle.

The present invention belongs to the field of medicine and specifically relates to the use of a combination of astemizole and terfenadine in the preparation of a drug for treating gastric cancer. The present invention finds that the antihistamine drug terfenadine can enhance the inhibitory effect of astemizole on gastric cancer AGS and HGC27 cells, significantly inhibiting the proliferation of AGS and HGC27 gastric cancer cells. Furthermore, terfenadine and astemizole can inhibit the migration of gastric cancer cells, induce apoptosis of gastric cancer cells, and block the cell cycle. The effect of terfenadine and astemizole in inhibiting the proliferation of gastric cancer cells is superior to that of the commonly used clinical anticancer drug 5-fluorouracil (5-FU), and the present invention has good application prospects in the treatment of gastric cancer.

1. The name of the design product: poster (terfenadine granules 2). 2. The use of the design product: for poster. 3. The design points of the design product: in the combination of shape and pattern. 4. The picture or photo that best indicates the design points: front view. 5. The design product is a flat product, and the rear view, left view, right view, top view and bottom view are omitted.

1. Name of the product in this design: Packaging Box (Tefenadine Granules). 2. Purpose of this design: For use in packaging boxes. 3. The key design elements of this product are the combination of shape, pattern, and color. 4. The image or photograph that best illustrates the design's key features: the front view. 5. The design for which protection is sought includes color.

The invention relates to the technical field of raw material medicine processing, in particular to cooling equipment for terfenadine raw material medicine, which comprises a device body, a front concave fixing plate and a rear concave fixing plate are fixedly mounted on two sides in the device body respectively, and arc-shaped power connection rings are fixedly mounted in the front concave fixing plate and the rear concave fixing plate. A motor drives a gear to rotate so as to act on a gear ring on the surface of a cooling charging barrel, the cooling charging barrel is driven to rotate on the inner sides of a front concave fixing plate and a rear concave fixing plate through a bearing ring, fins in the cooling charging barrel can raise materials, and a circulating fan enables dry and cold air in the condensation dryer to enter from an air inlet in the surface of the rear concave fixing plate; and then damp and hot air is discharged into the condensation drying machine through the exhaust port in the surface of the front concave fixing plate to be condensed and dried, so that the cooling efficiency is improved.