Application of p-hydroxyphenylacetic acid in prevention and/or treatment of cardiovascular diseases
A p-hydroxyphenylacetic acid and cardiovascular technology, applied in the field of medicine, can solve the urgent needs of safe and effective cardiovascular drug research and development, and achieve the effect of reducing venous congestion, reducing heart dilation, and increasing the length of blood vessels
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[0013] In order to facilitate a further understanding of the present invention, the examples provided below illustrate it in more detail. However, these examples are only for a better understanding of the invention and are not used to limit the scope or implementation principle of the invention, and the embodiments of the invention are not limited to the following content.
[0014] Effects of HPA on interbody vascular injury, inferior intestinal vein growth, heart failure and arrhythmia in zebrafish.
[0015] 1. Experimental animals
[0016] Animals used in blood vessel injury and inferior intestinal vein growth experiments of the present invention are vascular fluorescence transgenic Tg (fli-1:EGFP) zebrafish, animals used in heart failure experiments are AB wild-type zebrafish, and animals used in heart failure experiments are heart fluorescent transgenic Tg (cmlc2:GFP) line zebrafish. Breed under the conditions of 28°C, dark / light (10:14) photoperiod, and feed brine shrim...
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