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Method for measuringa viscoelastic parameter of human or animal organ

一种粘弹性、器官的技术，应用在器官运动/变化检测、无线电波测量系统、仪器等方向，能够解决信噪比低等问题，达到高信噪比、好脂肪变性、信噪比提高的效果

Active Publication Date: 2018-02-02
ECHOSENS SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0008] However, due to the high attenuation of ultrasound pulses in the subcutaneous tissue (especially in adipose tissue) and the tissue to be measured itself, the signal-to-noise ratio in existing measurement techniques can be very low, especially in obese patients (such Human liver is usually fatty)

Method used

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  • Method for measuringa viscoelastic parameter of human or animal organ
  • Method for measuringa viscoelastic parameter of human or animal organ
  • Method for measuringa viscoelastic parameter of human or animal organ

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Embodiment Construction

[0060] figure 1 The steps of the first method according to the invention are described. Method 1 here consists of three steps:

[0061] -EM-US transmitting step, a series of ultrasonic beams propagating through the organ to be investigated are transmitted by an ultrasonic transducer US;

[0062] - REC recording step, the reflected ultrasound signal is recorded by this same ultrasound transducer US;

[0063] - a DET determination step of determining at least one viscoelastic parameter in the organ based on the recorded signals.

[0064] Advantageously, this embodiment measures a parameter such as the attenuation of an ultrasound signal. In the human liver, this parameter is especially important as it correlates with the presence of fatty liver.

[0065] figure 2 and image 3 The structure and characteristics of the ultrasound beam are shown in .

[0066] figure 2 The illustrated ultrasonic beams include K groups of ultrasonic beams. For example, if figure 2 As show...

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Abstract

The present invention relates to a method for measuring at least one viscoelastic parameter of a human or animal organ, said method having the following steps: emission of a plurality of ultrasonic shots by an ultrasonic transducer, said ultrasonic shots propagating in the organ that is to be characterized; reception by the ultrasonic transducer and recording of the reflected ultrasonic signals; determination of at least one viscoelastic parameter of the organ on the basis of the recorded ultrasonic signals; the plurality of ultrasonic shots is formed by K groups of shots, said groups being separated temporally, K being greater than or equal to 1; each of the K groups of ultrasonic shots is formed by the repetition, with a rate of PRF2, of MK blocks of ultrasonic shots, MK being greater than or equal to 1; each of said MK blocks is composed of N ultrasonic shots, N being greater than or equal to 1, PRF1 being the rate of emission of the N shots when N is chosen greater than 1; the N ultrasonic shots are distributed over P frequencies, P being between 1 and N, at least two ultrasonic shots belonging to two different blocks having different frequencies.

Description

technical field [0001] The invention relates to the technical field of measuring viscoelastic parameters of biological tissues. In particular, the present invention relates to a method for measuring viscoelastic parameters using ultrasonic pulses of different frequencies. Background technique [0002] A number of different non-invasive techniques have been developed for measuring viscoelastic parameters of human or animal organs. [0003] Among these techniques, vibration-controlled transient elastography (VCTE) is particularly effective in the diagnosis of soft tissue, especially human liver diseases. For example, the applicant has developed and commercialized a product called Fibroscan TM device, as a benchmark device for the diagnosis and monitoring of liver fibrosis. This device is schematically described in patents EP 1 169 636 and EP 1531 733 filed by the applicant. Liver fibrosis, the loss of elasticity of liver tissue, is a secondary symptom of diseases such as h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B8/00
CPCA61B8/08A61B8/44A61B8/4483A61B8/485A61B8/085A61B8/5207A61B8/5223A61B8/54G01S7/52042G01S7/52036G01S7/52022
Inventor 斯蒂芬·奥迪尔洛朗·桑德兰
Owner ECHOSENS SA
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