Intravascular stent
A technology of vascular stents and seeds, applied in the field of vascular stents, can solve the problems of affecting drug efficacy, slow release, and drug effect effects, and achieve the effects of prolonging release time, improving release efficiency, good biocompatibility and degradability
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[0020] Specific Example 1: A cyclodextrin grafted modified polymalic acid, the preparation steps are as follows:
[0021] Step 1. Inoculate the polymalic acid strain on the plate, culture at 25°C for 2 hours, and pick a single colony for activation;
[0022] Step 2. Seed culture, inoculate the above-mentioned activated strains into the seed medium, the culture temperature is 26°C, the rotation speed is 300 rpm, and the culture time is 48 hours;
[0023] Step 3. Expanded cultivation. The seed solution is cultivated in an expanded medium at an inoculum of 10% at a temperature of 26°C, a rotation speed of 300 revolutions per minute, and a cultivation time of 72 hours;
[0024] Step 4. Inoculate the expanded culture solution into a fermentor at a 5% inoculum amount for culture, the culture temperature is 30°C, the culture time is 10 days, and the fermentation speed is 300 rpm;
[0025] Step 5. Take the fermentation broth, collect the cells by centrifugation, heat it in a chloroform water ba...
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