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Method and kit for screening early-stage non-small cell cancer

A non-small cell lung cancer and kit technology, applied in the field of tumor screening, can solve the problems that lung cancer cannot be ruled out, and early non-small cell lung cancer cannot be accurately predicted, so as to achieve the effect of improving accuracy

Active Publication Date: 2018-03-06
华明康生物科技(深圳)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, negative CYFRA21-1 does not rule out the possibility of lung cancer
The combination of cytokeratin 19 (CYFRA21-1) and carcinoembryonic antigen (CEA) cannot accurately predict early non-small cell lung cancer

Method used

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  • Method and kit for screening early-stage non-small cell cancer
  • Method and kit for screening early-stage non-small cell cancer
  • Method and kit for screening early-stage non-small cell cancer

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Embodiment Construction

[0023] Before introducing the present invention in detail, first introduce the symptoms of lung cancer and the existing methods and limitations of detecting lung cancer.

[0024] Symptoms of lung cancer include: cough occurs earlier in central lung cancer, often with paroxysmal, irritating dry cough as the first symptom, no sputum or only a small amount of white foamy mucus sputum. Hemoptysis, intermittent or persistent bloody sputum, lung cancer generally rarely causes massive hemoptysis. If the lesion involves the pleura or chest wall, there may be persistent, fixed and severe chest pain. When central lung cancer causes airway obstruction, there may be chest tightness and shortness of breath. In the late stage, with the compression of the trachea and bronchi, dyspnea may be severe, and fever is often secondary to bronchial and pulmonary infections. Systemic symptoms may include signs of weight loss, fatigue, loss of appetite, and weight loss, and there may be no positive s...

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Abstract

The present invention discloses a method and kit for screening early-stage non-small cell cancer. According to the method, early-stage non-small cell cancer is screened through combined detection of keratanase protein (YKL-40), cytokeratin 19 (CYFRA21-1) and carcinoembryonic antigen (CEA). With the method, the early-stage non-small cell cancer prediction accuracy can be improved.

Description

technical field [0001] The invention relates to the technical field of tumor screening, in particular to an early non-small cell lung cancer screening method and a kit. Background technique [0002] Lung cancer is a common malignant tumor in my country, and it is found in clinical practice that there are more male lung cancer patients than female patients. According to the 2012 data of the International Agency for Research on Cancer, the number of lung cancer patients in 2012 was 6.53 million, including 4.59 million men and 1.93 million women. Lung cancer ranks first in cancer incidence and death in the country. [0003] The cause of lung cancer is not fully understood. Its etiology may be related to smoking, air pollution, ionizing radiation, occupation (asbestos, monument, asphalt, smoke, etc.). Lung cancer is generally divided into two categories: non-small cell lung cancer (NSCLC for short) and small cell lung cancer (SCLC for short). There are many inspection and de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/68G01N33/574
CPCG01N33/57423G01N33/57473G01N33/57484G01N33/6803
Inventor 何传华李作生王岳鹏李大伟王朝阳仇家舟何浩然
Owner 华明康生物科技(深圳)有限公司
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