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Liquid bacterial interception experiment method as well as liquid bacterial interception experiment system-air filter with normal pore diameter of 0.2 [m]um

A technology of air filter and nominal pore size, which is applied in the field of medical air filter liquid bacteria interception detection test system, can solve the problems of low precision of filter liquid and the like

Pending Publication Date: 2018-05-01
山东省医疗器械产品质量检验中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the different filtration mechanisms, the liquid precision of the filter is lower than that of the gas. It has been proved that the filter that can intercept phage / virus in the aerosol challenge can not intercept the phage / virus in the liquid challenge.

Method used

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  • Liquid bacterial interception experiment method as well as liquid bacterial interception experiment system-air filter with normal pore diameter of 0.2 [m]um
  • Liquid bacterial interception experiment method as well as liquid bacterial interception experiment system-air filter with normal pore diameter of 0.2 [m]um
  • Liquid bacterial interception experiment method as well as liquid bacterial interception experiment system-air filter with normal pore diameter of 0.2 [m]um

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Embodiment Construction

[0015] The liquid bacterial interception test system of the present invention-the air filter with a nominal aperture of 0.2 μm includes a constant pressure tank 202, the top of the constant pressure tank 202 communicates with the air outlet of the air pump 201 through an inlet pipe 209, and a pressure gauge is set on the constant pressure tank 202 204, the constant pressure tank 202 is equipped with challenge bacteria liquid, and the constant pressure tank 202 is connected with the inlet of the air filter 206 with a nominal pore size of 0.2 μm for testing through a liquid outlet pipe 210, and the air filter 206 with a nominal pore size of 0.2 μm is located in the filter In the liquid outlet collection bottle 208 , a flow valve 205 is arranged on the liquid outlet pipe 210 , and the inlet of the liquid outlet pipe 210 is located at the bottom of the constant pressure tank 202 . Before the test, inject no less than 2400mL of Brevundimonas diminatus ATCC 19146 bacteria suspension ...

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Abstract

The invention relates to a liquid bacterial interception experiment method as well as a liquid bacterial interception experiment system-air filter with normal pore diameter of 0.2 [mu]m. The liquid bacterial interception experiment system-air filter with normal pore diameter of 0.2 [mu]m comprises a constant-pressure tank; the top of the constant-pressure tank is communicated with a gas outlet ofa gas pump through a gas inlet pipe; a pressure gauge is arranged on the constant-pressure tank; the constant-pressure tank is filled with challenge bacterial liquid; the constant-pressure tank is communicated with the inlet of the tested air filter with normal pore diameter of 0.2 [mu]m; the air filter with normal pore diameter of 0.2 [mu]m is positioned in a percolate collecting bottle; a flow valve is arranged on a liquid outlet pipe; the inlet of the liquid outlet pipe is positioned at the bottom of the constant-pressure tank. The liquid bacterial interception experiment system-air filterwith normal pore diameter of 0.2 [mu]m has the following advantages: the filtering effect of the to-be-tested air filter with normal pore diameter of 0.2 [mu]m under the worst condition can be tested,the system can help people to evaluate the bacterial interception ability of the air filter, and the rigorous use requirements of medical equipment such as a transfusion device and a blood transfusion device can be met.

Description

technical field [0001] The invention relates to a liquid bacterial interception test system and method of a medical air filter, in particular to a liquid bacterial interception test method and system - an air filter with a nominal pore size of 0.2 μm. Background technique [0002] At present, there are several methods for evaluating the retention capacity of gas filters, mainly including liquid bacterial retention test, aerosol bacterial retention test and aerosol virus retention test, etc. The liquid bacterial interception test is to pre-wet the hydrophobic filter membrane with a low surface tension liquid, and then refer to the bacterial interception test method of the sterile-grade liquid filter / membrane, using a diameter of about 0.3μm ~ 0.4μm, long The bacterial suspension of Brevundimonas diminuta (ATCC 19146) with a diameter of about 0.6 μm ~ 1.0 μm was challenged. Correspondingly, with reference to liquid sterilization and filtration, most manufacturers currently la...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/36C12M1/34C12M1/12C12M1/04C12Q1/06
CPCC12M29/04C12M29/08C12M41/00C12M41/40C12Q1/06
Inventor 施燕平王文庆郝树彬秦杰王科镭
Owner 山东省医疗器械产品质量检验中心