Product for treating leucoderma, and usage method and application thereof

Abstract

The invention discloses a product for treating leucoderma, and a usage method and application thereof. The product comprises external secretory bodies of a human umbilical cord mesenchymal stem cell source and human autotransplantation skin cells. Through immunoregulation effect and regeneration repairing function of the external secretory bodies of the umbilical cord mesenchymal stem cell source,negative regulation of autoimmunity of patients suffering from the leucoderma is realized, attack of the autoimmunity system to melanocytes is inhibited, survival of the melanocytes and keratinocytesis promoted, normal melanin secretion functions of the melanocytes are recovered, and rapid color recovery and skin lesion repairing of leucoderma skin lesions are realized radically.

Description

technical field [0001] The invention relates to the field of autoimmune regulation related to vitiligo, in particular to a product for treating vitiligo and its use method and application. Background technique [0002] Vitiligo (vitiligo) is a common skin depigmentation disease caused by the reduction or loss of functional melanocytes in the skin and / or hair follicles. The prevalence of the disease in the world is 0.5% to 2%. The main symptoms Localized or generalized skin leukoplakia is caused by a large area of ​​melanin deficiency. The etiology and pathogenesis of vitiligo have not yet been fully elucidated. Mental and nervous, oxidative stress and other aspects: In 1977, Hertz first proposed the concept of vitiligo autoimmunity. Naughton et al. found that the serum of most patients with vitiligo contains antibodies against black cell surface antigens, and the degree of skin depigmentation is related to The antibody level of melanocyte surface antigen is closely related....

AI Technical Summary

Problems solved by technology

[0003] The key point in the treatment of vitiligo is to control the damage of its own immune system to melanocytes and stimulate the migration of melanocytes from the surrounding skin and melanin-rich layer to the damaged area. The current treatment methods mainly include physical therapy, drugs, etc. Treatment, transplant surgery, etc. Physical therapy includes phototherapy, etc. Phototherapy has a moderate effect and cannot fundamentally treat vitiligo. Drug therapy is mainly hormone and immunosuppressant therapy, but long-term use has serious side effects, such as wound atrophy, wound streaking, Telangiectasia and a series of systemic side effects, etc., skin or skin cell transplantation can only improve the skin lesion state and pigmentation in a short time, but cannot fundamentally improve the long-term treatment effect of vitiligo. To change the long-term treatment effect of vitiligo, we must start from Fundamentally change or correct the autoimmune imbalance in the body, prevent the implanted skin or skin cells and regenerated skin cells and functions from being attacked and destroyed by the autoimmune system again, fundamentally solve the problem of vitiligo skin damage, and promote wound healing And the long-term survival of implanted and regenerated skin cells, to achieve a real cure for vitiligo

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