Flow control method and device, analytical instrument, and computer-readable storage medium
A technology of flow control and high-pressure constant-flow pump, which is applied in the field of medical equipment, can solve the problems of increasing the dead volume of mobile phase and reducing the accuracy of sample analysis, and achieve the effect of reducing instantaneous flow fluctuation
Active Publication Date: 2020-08-28
MACCURA MEDICAL INSTR CO LTD
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Problems solved by technology
However, increasing the number of plungers or increasing the damper will increase the dead volume of the mobile phase, that is, the void volume in the column that is not occupied by the stationary phase, resulting in a decrease in the analysis accuracy of the sample
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[0038] Features and exemplary embodiments of various aspects of embodiments of the present invention will be described in detail below. In the following detailed description, numerous specific details are set forth in order to provide a thorough understanding of embodiments of the invention.
[0039] Embodiments of the present invention provide a flow control method and device, an analysis instrument, and a computer-readable storage medium, which are used in a high-pressure constant-flow pump of a liquid chromatograph or a glycated hemoglobin analyzer. The high pressure constant flow pump is a reciprocating double cam plunger pump controlled by a microcomputer, which has the characteristics of convenient operation, stable flow rate, small pressure pulsation and low failure rate.
[0040] The output end of the high-pressure constant-flow pump is connected to the chromatographic column, and can deliver the mobile phase liquid to the chromatographic column. The high-pressure con...
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The embodiment of the invention discloses a flow control method and device, an analysis instrument, and a computer-readable storage medium. The flow control method includes: obtaining a first curve of the high-pressure constant-flow pump, the first curve is used to represent the relationship of the output flow of the high-pressure constant-flow pump with time; obtaining one or more Characteristic spectrum, each characteristic spectrum corresponds to a peak or trough in the first curve; according to one or more characteristic spectra, adjust the speed of the plunger in the high-pressure constant-flow pump, so that the speed of the plunger in a single stroke cycle tends to be constant . By adopting the technical solutions in the embodiments of the present invention, the instantaneous flow fluctuation of the high-pressure constant-flow pump can be reduced without increasing the number of plungers or adding dampers.
Description
technical field [0001] The invention relates to the field of medical devices, in particular to a flow control method and device, an analysis instrument and a computer-readable storage medium. Background technique [0002] Compositional analysis is the main purpose of medical analytical instruments, such as hemoglobin analyzers. The output end of the high-pressure constant-flow pump is connected to the chromatographic column. The working principle of the high-pressure constant-flow pump is: to use the reciprocating motion of the plunger in the high-pressure constant-flow pump to make the high-pressure constant-flow pump alternately absorb and discharge liquid in each stroke cycle , to input the mobile phase from the reagent bottle to the column. However, the reciprocating motion of the plunger will inevitably cause instantaneous flow fluctuations, which will cause the noise of the chromatogram to increase and reduce the analysis accuracy of the sample. [0003] In order to ...
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IPC IPC(8): G06K9/00
CPCG06F2218/10G06F2218/08
Inventor 杨建华陆辉
Owner MACCURA MEDICAL INSTR CO LTD