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Diffusion Tensor Estimation Method of Left Ventricle of Human Heart Based on Structural Prior Information

A technology of prior information and diffusion tensor, applied in the field of left ventricular diffusion tensor estimation of human heart, can solve the problems of noise influence, poor accuracy of left ventricular diffusion tensor estimation results, etc., to achieve improved accuracy, diffusion anisotropy Improve, improve the effect of accuracy

Active Publication Date: 2022-05-06
BOHAI UNIV
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Problems solved by technology

[0005] The present invention provides a human heart left ventricular diffusion tensor estimation method based on structural prior information, which solves the problem that the existing diffusion tensor estimation method is used for left ventricular diffusion tensor estimation with poor accuracy and is seriously affected by noise

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  • Diffusion Tensor Estimation Method of Left Ventricle of Human Heart Based on Structural Prior Information
  • Diffusion Tensor Estimation Method of Left Ventricle of Human Heart Based on Structural Prior Information
  • Diffusion Tensor Estimation Method of Left Ventricle of Human Heart Based on Structural Prior Information

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Embodiment

[0060] In this embodiment, the diffusion tensor model method is used to simulate and generate a set of MRI diffusion-weighted image simulation data with a resolution of 32×32 in short-axis slices of the left ventricle of the heart. This set of data includes 30 MRI images with different diffusion gradient directions. Diffusion weighted image, the value of diffusion sensitivity factor b is 1000, and the three eigenvalues ​​of the tensor are (1.2, 0.3, 0.3)×10 -3 mm 2 / s, the spiral angle of the simulated left ventricular short-axis slice from epicardium to endocardium changes linearly from -60 degrees to 60 degrees, and the transverse angle is 0 degrees. The actual diffusion tensor of each voxel is as figure 1 As shown, each ellipsoid in the figure represents the diffusion tensor of the voxel where it is located. The direction of the major axis of the ellipsoid reflects the direction of the fiber in the voxel. The lengths of the three axes of the ellipsoid reflect the three dim...

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Abstract

The invention relates to the technical field of cardiac magnetic resonance diffusion tensor imaging signal processing, in particular to a method for estimating the diffusion tensor of the left ventricle of the human heart based on structural prior information. The prior fiber orientation is obtained by fitting the quantitative estimation results, and then the objective function based on the smoothness restriction of the neighborhood tensor and the prior fiber orientation restriction is constructed, and finally the objective function minimization problem with positive definite restriction is solved to obtain the estimation result of the diffusion tensor. . The estimation result is more realistic and more accurate; it can effectively improve the estimation accuracy of the left ventricular diffusion tensor of the human heart. Compared with the classical linear least squares method, the main feature of the diffusion tensor estimated by the method of the present invention The direction (main diffusion direction) accuracy is improved by about 31%, and the diffusion anisotropy is improved by about 14%.

Description

technical field [0001] The invention relates to the technical field of cardiac magnetic resonance diffusion tensor imaging signal processing, in particular to a method for estimating the left ventricle diffusion tensor of human heart based on structural prior information. Background technique [0002] Magnetic resonance diffusion imaging is currently the only non-invasive method that can measure the diffusion information of water molecules in living tissue. The diffusion movement of water molecules in the tissue is limited by the microstructure of the tissue. Therefore, the microstructure of the tissue can be reconstructed by measuring the diffusion information of water molecules . This method has the advantages of non-invasiveness and no need for contrast agents, and has attracted great attention in both theoretical research and clinical practice. Initially, diffusion magnetic resonance imaging was primarily used to image white matter fiber structures. In recent years, wi...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/00G06F17/16A61B5/055A61B5/00
CPCA61B5/055G06F17/16G06T7/0012A61B5/72G06T2207/30048G06T2207/10088
Inventor 楚春雨张宇峰梁洪晶
Owner BOHAI UNIV