Composition with hypolipidemic effect and preparation method thereof

A composition and blood lipid-lowering technology, applied in the direction of medical preparations containing active ingredients, drug combinations, applications, etc., can solve problems such as increased blood pressure and blood pressure rebound

Active Publication Date: 2021-04-20
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine does not solve the pathological factors that cause blood pressure to rise. Once the drug is stopped, the blood pressure will rebound quickly and the patient must take the drug for life

Method used

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  • Composition with hypolipidemic effect and preparation method thereof
  • Composition with hypolipidemic effect and preparation method thereof
  • Composition with hypolipidemic effect and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Weigh the following raw materials in parts by weight: 10 parts of cistanche, 5 parts of tartary buckwheat, 2 parts of green tea, 1 part of lotus leaf, and 2 parts of ebony plum; the above raw materials are mixed, and water of 12 times the total weight of raw materials is added as an extraction solvent. Extract twice at 95°C, each time for 1.5h, filter, and combine the filtrate; the filtrate is concentrated under reduced pressure at 70°C and a relative vacuum of -0.07MPa to obtain a concentrated solution with a density of 1.1g / mL, which is spray-dried and controlled The hot air inlet temperature during spray drying is 180° C. to obtain the material; the material is crushed and passed through an 80-mesh sieve to obtain the traditional Chinese medicine composition.

Embodiment 2

[0029] Weigh the following raw materials in parts by weight: 20 parts of cistanche, 5 parts of tartary buckwheat, 3 parts of green tea, 1 part of lotus leaf, and 2 parts of ebony plum; the above raw materials are mixed, and water of 14 times the total weight of raw materials is added as an extraction solvent. Extract at 100°C for 3 hours, and obtain the filtrate after filtration; the filtrate is concentrated under reduced pressure at 60°C and a relative vacuum of -0.09MPa to obtain a concentrated solution with a density of 1.2g / mL, and the concentrated solution is stored at 80°C and a relative vacuum of -0.07MPa Vacuum drying, crushing through an 80-mesh sieve to obtain a traditional Chinese medicine composition.

Embodiment 3

[0031] Weigh the following raw materials in parts by weight: 12 parts of cistanche, 6 parts of tartary buckwheat, 2 parts of green tea, 2 parts of lotus leaf, and 4 parts of ebony plum; the above raw materials are mixed, and water of 16 times the total weight of raw materials is added as an extraction solvent. Extract at 95°C for 3 times, each time for 1h, filter, and combine the filtrate; the filtrate is concentrated under reduced pressure at 70°C and a relative vacuum of -0.08MPa to obtain a concentrated solution with a density of 1.08g / mL. The concentrated solution is spray-dried and sprayed under control. The hot air inlet temperature during drying is 200° C. to obtain the material; the material is crushed and passed through an 80-mesh sieve to obtain a traditional Chinese medicine composition.

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Abstract

The invention discloses a composition with hypolipidemic effect. The composition is made of the following raw materials in parts by weight: 5-30 parts of cistanche, 1-20 parts of tartary buckwheat, 1-20 parts of green tea, and 1 part of lotus leaf ~20 parts, ebony 0.2~15 parts. The invention also discloses the application of the composition in the preparation of medicine or health food with hypolipidemic effect. The composition of the present invention is composed of Cistanche deserticola, tartary buckwheat, green tea, lotus leaf and ebony. As an adjuvant drug, the whole prescription complements each other, so as to achieve the scientific compatibility of the king and minister, and effectively enrich the active ingredients with the effect of lowering blood lipids, such as flavonoids, polyphenols, active polysaccharides, alkaloids, etc. in the five-flavored raw materials. Inhibit endogenous lipid synthesis, promote lipid transport and excretion, and regulate lipid metabolism to play a synergistic role in lowering blood lipids.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine health care products, in particular to a composition with hypolipidemic effect and a preparation method thereof. Background technique [0002] Hyperlipidemia is a common and frequently occurring metabolic disease, which refers to excessive blood lipid levels, which can directly cause some diseases that seriously endanger human health, such as atherosclerosis, coronary heart disease, pancreatitis, etc. Hyperlipidemia is common in middle-aged and elderly people, but with changes in diet structure and increased alcohol consumption, the prevalence rate among young people is also increasing year by year. Therefore, people pay more and more attention to the prevention and treatment of hyperlipidemia. [0003] There is no disease name for hyperlipidemia in traditional Chinese medicine. Hyperlipidemia is believed to be caused by deficiency in origin and excess in superficiality, and b...

Claims

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Application Information

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Patent Type & AuthorityPatents(China)
IPC IPC(8): A23L33/105A61K36/82A61P3/06
CPCA23V2002/00A61K36/62A61K36/64A61K36/70A61K36/736A61K36/82A61K2236/331A61K2236/39A61K2236/51A23L33/105A61P3/06A61K2300/00A23V2200/30A23V2250/21
Inventor萧伟邓辰辰王婧刘世娟许明君高如意柏伟荣
OwnerJIANGSU KANION PHARMA CO LTD