Eye anti-wrinkle gel containing pterostilbene compound capable of self-providing weak acid environment and preparation method of eye anti-wrinkle gel

Abstract

The invention discloses eye anti-wrinkle gel containing a pterostilbene compound capable of self-providing a weak acid environment. The eye anti-wrinkle gel is characterized by being prepared from thefollowing main components: 2 to 10 mg / ml of pterostilbene, 30 to 60 mg / ml of rebaudioside A, 5 to 12 mg / ml of glycyrrhizic acid, and 1 to 5 mg / ml of sodium hyaluronate. The preparation method comprises the following steps: (1) fully dissolving the pterostilbene into ethanol, mixing the rebaudioside A with the glycyrrhizic acid according to a proportion, dissolving the mixture in the pterostilbene-dissolved ethanol solution, and spinning the ethanol solution till the ethanol solution is dry, thus obtaining solid powder; (2) immersing the sodium hyaluronate in water over night till the sodium hyaluronate is completely dissolved for later use; (3) adding the solid powder obtained in Step (1) into the hyaluronate solution obtained in Step (2), and stirring the solution till the solid powder is completely dissolved. The dissolvability of the pterostilbene in the gel prepared with the method is obviously improved, so that the pterostilbene can be absorbed by eye skin more easily to exert aneye protecting effect. The eye anti-wrinkle gel is easy to prepare, and the pterostilbene compound-containing eye gel is extremely high in anti-oxidization capacity, can self-provide the weak acid environment and obviously improve the state of the eye skin, and is irritant.

Description

technical field [0001] The invention relates to cosmetic products frequently used in daily life, in particular to an anti-wrinkle eye gel containing pterostilbene complex capable of providing a weakly acidic environment by itself and a preparation method thereof. Background technique [0002] With age, the skin ages, the epidermal tissue becomes dry and thin, and the collagen and elastic fibers in the dermis are insufficiently replenished and become thinner, and wrinkles are formed due to the loss of mesh support. At the same time, the eye skin is affected by the external environment (such as ultraviolet rays, etc.), forming free radicals, free radicals destroy collagen and active substances in normal cell membrane tissues, and oxidize cells to form small fine lines and wrinkles. The formation of eye wrinkles is the most important body surface feature of skin aging. At the same time, the surface of the skin is weakly acidic. Only when the skin is in the normal pH range, tha...

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Problems solved by technology

But pterostilbene has the following deficiencies, which seriously affect its development and utilization: (1) poor water solubility, pterostilbene in the water phase at 20 ° C, the solubility in water is about 0.03mg / ml; (2) molecular structure is unstable, pterostilbene Contain phenolic hydroxyl in the molecular structure of stilbene, and phenolic hydroxyl is extremely unstable, and this has just determined that the stability of pterostilbene is extremely poor, especially extremely unstable in aqueous solution, easily oxidized; (3) half-life period is short, and biofilm permeability is poor , the mucous membrane bioavailability including transdermal, ophthalmic, etc. is extremely low

Above-mentioned these deficiencies have seriously limited the application of pterostilbene in fields such as cosmetics

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