External application of anti-inflammation and detumescence traditional Chinese medicine ointment

A technology of traditional Chinese medicine ointment and raw material medicine, which is applied in the direction of medical formula, drug combination, plant raw materials, etc., and can solve problems such as ignoring toxicity and irritation, poor transdermal absorption effect, and destroying active ingredients of medicinal materials

Active Publication Date: 2021-04-20
JIANGSU QILIKANG SKIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] But the traditional external application of anti-inflammatory and detumescent Chinese medicine ointment has the following disadvantages: (1) only consider the efficacy of Chinese medicine when preparing the ointment, and ignore its toxicity and irritation, which will aggravate the patient's discomfort; (2) the traditional external application ointment

Method used

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  • External application of anti-inflammation and detumescence traditional Chinese medicine ointment
  • External application of anti-inflammation and detumescence traditional Chinese medicine ointment
  • External application of anti-inflammation and detumescence traditional Chinese medicine ointment

Examples

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Effect test

example 1

[0029] An anti-inflammatory and anti-tumor traditional Chinese medicine ointment for external application, which is composed of the following components in proportion by weight: 15 parts of seabuckthorn fruit stones; 10 parts of Phellodendron cortex; 8 parts of raw land; parts; pumpkin seeds 5 parts; Chuanxiong 3 parts; VB 5 3 parts; 3 parts of skin penetration enhancer.

[0030] Wherein, the skin penetration enhancer includes 30wt% menthol, 40wt% borneol, 20wt% PEG400 and 10wt% octanol.

[0031] Among them, the seabuckthorn fruit core, Cortex Phellodendri, Shengdi, Uncaria, and Rhizoma Chuanxiong were respectively crushed to an average particle size of 20 μm, mixed, and then 85% ethanol of 5 times the amount of the traditional Chinese medicine mixture was used as a solvent, and refluxed at 80°C to extract 3 time, each extracting 1h; the chamomile, forsythia, and pumpkin seeds were crushed to 28 μm respectively, mixed, and then mixed with 70% ethanol that was 4 times the vol...

example 2

[0035] An anti-inflammatory and anti-tumor traditional Chinese medicine ointment for external application, which is composed of the following components in proportion by weight: 20 parts of seabuckthorn fruit stones; 15 parts of Phellodendron cortex; 10 parts of pumpkin seeds; 7 parts of Chuanxiong; VB 5 5 parts; 5 parts of skin penetration enhancer.

[0036] Wherein, the skin penetration enhancer includes 40wt% menthol, 35wt% borneol, 15wt% PEG600 and 10wt% octanol.

[0037] Among them, the seabuckthorn fruit core, Phellodendron cork, Shengdi, Uncaria, and Rhizoma Chuanxiong were respectively crushed to an average particle size of 25 μm, mixed, and then 85% ethanol of 8 times the amount of the traditional Chinese medicine mixture was used as a solvent, and refluxed at 80°C to extract 3 times, each extraction time is 2h. ; The chamomile, forsythia, and pumpkin seeds are respectively crushed to 32 μm, mixed, and then 70% ethanol with 5 times the volume of the mixture of cham...

example 3

[0041] An anti-inflammatory and anti-tumor traditional Chinese medicine ointment for external application, which is composed of the following components in proportion by weight: 16 parts of seabuckthorn fruit stones; 12 parts of Phellodendron cortex; 11 parts of raw land; 9 parts of pumpkin seeds; 3 parts of Chuanxiong; VB 5 5 parts; 4 parts of skin penetration enhancer.

[0042] Wherein, the skin penetration enhancer includes 35wt% menthol, 35wt% borneol, 15wt% PEG500 and 15wt% octanol.

[0043]Among them, the seabuckthorn fruit core, Phellodendron cork, Shengdi, Uncaria, and Rhizoma Chuanxiong were respectively crushed to an average particle size of 23 μm, mixed, and then 7 times the amount of 85% ethanol of the traditional Chinese medicine mixture was used as a solvent, and refluxed at 80°C to extract 3 times, the extraction time is 2h, 1.5h and 1h respectively; the chamomile flower, forsythia and pumpkin seeds are respectively crushed to 30 μm, mixed, and then sequential...

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Abstract

A traditional Chinese medicinal ointment for external application of anti-inflammatory and detumescence, which consists of the following components in parts by weight: 15-20 parts of seabuckthorn fruit stones, 10-15 parts of Cortex Phellodendri, 8-12 parts of Rehmannia glutinosa, 8-12 parts of chamomile, Rhizoma 5-15 parts, Uncaria 5-15 parts, Pumpkin seeds 5-10 parts, Rhizoma Chuanxiong 3-7 parts, VB5 3-5 parts, Transdermal accelerator 3-5 parts. Wherein, the skin penetration enhancer includes 30-40wt% menthol, 30-40wt% borneol, 15-20wt% PEG and 10-15wt% octanol.

Description

technical field [0001] The invention relates to a traditional Chinese medicine ointment. More specifically, the present invention relates to a traditional Chinese medicine ointment with anti-inflammation and detumescence for external application. Background technique [0002] Traditional Chinese medicine ointment for external use is an external semi-solid dosage form that is made by mixing medicinal material extracts with a suitable medium and is easy to apply on the skin surface. It has the advantages of good adhesion, spreadability, and convenient use and portability. Traditional Chinese medicine ointment uses the coordination of drugs to form a large compound of multi-flavored drugs to exert the good effect of drugs. The plaster affixed to the body surface stimulates nerve endings, dilates blood vessels through reflection, and promotes local blood circulation. Circulation, improve the nutrition of surrounding tissues, so as to achieve the purpose of detumescence, anti-in...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K36/756A61K36/74A61K36/634A61K36/42A61K36/28A61K36/236A61K36/185A61P17/00
CPCA61K36/185A61K36/236A61K36/28A61K36/42A61K36/634A61K36/74A61K36/756A61K36/804A61P17/00
Inventor 吴克
Owner JIANGSU QILIKANG SKIN PHARMA
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