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Pharmaceutical composition for treating premature ejaculation

A technology of composition and medicine, which is applied in the field of pharmaceutical composition for treating premature ejaculation, can solve the problems of high price, prolonging ejaculation latency period, and relatively large side effects, and achieve reasonable proportioning, prolonging male sexual life time, and reducing side effects Effect

Inactive Publication Date: 2018-10-09
王大伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, oral drug therapy is one of the main methods for the treatment of premature ejaculation. Oral drug therapy mainly uses serotonin reuptake inhibitors. Dapoxetine has been marketed in China. It mainly prolongs the ejaculation latency period and has relatively large side effects. and expensive

Method used

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  • Pharmaceutical composition for treating premature ejaculation
  • Pharmaceutical composition for treating premature ejaculation
  • Pharmaceutical composition for treating premature ejaculation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] When the patient takes orally the unit dosage form of the pharmaceutical composition is 1 mg of Pagiline and 10 mg of Fluoxetine, 2 times / day; when the marked effect appears, the frequency of taking the medicine is changed to 1 time / day after continuing to take the medicine for half a month; Pagiline 0.5mg, fluoxetine 5mg, 1 time / day; the frequency of taking the medicine in another week was changed to 1 time / every other day, and the medicine was stopped completely in another week. The statistics of the final treatment effect are shown in Table 2:

[0047] Table 2

[0048]

Embodiment 2

[0050] When the patient takes the pharmaceutical composition orally, the unit dosage form is Pagiline 2mg, Fluoxetine 10mg, 2 times / day; when the marked effect appears, the frequency of taking the medicine is changed to 1 time / day after continuing to take the medicine for half a month; Pagiline 1mg, fluoxetine 5mg, 1 time / day; the frequency of taking the medicine in another week was changed to 1 time / every other day, and the medicine was stopped completely in another week. The statistics of the final treatment effect are shown in Table 3:

[0051] table 3

[0052]

Embodiment 3

[0054]When the patient takes the pharmaceutical composition orally, the unit dosage form is Pagiline 10mg, Fluoxetine 10mg, 2 times / day; when the marked effect appears, continue to take the medicine for half a month and then change the dosage to 1 time / day; Pagiline 5mg, fluoxetine 5mg, 1 time / day; the frequency of taking the medicine in another week was changed to 1 time / every other day, and the medicine was stopped completely in another week. The statistics of the final treatment effect are shown in Table 4:

[0055] Table 4

[0056]

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PUM

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Abstract

The invention relates to a pharmaceutical composition and discloses the pharmaceutical composition for treating premature ejaculation. The pharmaceutical composition includes Pargyline as an active component or a medicinal salt thereof, fluoxetine or the medicinal salt thereof, and optional pharmaceutical adjuvants, wherein the weight ratio of the Pargyline or the medicinal salt thereof to the fluoxetine or the medicinal salt thereof is 0.1:10-10:0.1, preferably 1:10-10:1, and the medicinal salt is hydrochloride. The pharmaceutical composition is an oral preparation; a unit dosage form of theoral preparation includes the Pargyline of 0.1-10 mg and the fluoxetine of 0.1-10 mg; and the unit dosage form of the oral preparation includes the Pargyline of 1-10 mg and the fluoxetine of 1-10 mg.The pharmaceutical composition has the advantages of low medicine cost and small side-effect.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating premature ejaculation. Background technique [0002] Premature ejaculation is the most common ejaculatory dysfunction, and the incidence rate accounts for more than 1 / 3 of adult men. The clinical manifestation of premature ejaculation is mainly excessive ejaculation. After the man erects, he touches or just touches the vulva of the woman, or for a short time, he ejaculates before reaching orgasm. The causes of premature ejaculation can be divided into psychological premature ejaculation, organic premature ejaculation and premature ejaculation caused by other reasons, among which psychological premature ejaculation is the main cause of premature ejaculation. [0003] At present, oral drug therapy is one of the main methods for the treatment of premature ejaculation. Oral drug therapy mainly uses serotonin reuptake inhibitors. Dapoxetine has...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/138A61K31/137A61P15/00
CPCA61K31/138A61K31/137A61K2300/00
Inventor 王大伟
Owner 王大伟