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Pharmaceutical composition used for treating premature ejaculation

A technology of composition and medicine, which is applied in the field of pharmaceutical composition for treating premature ejaculation, can solve the problems of relatively large side effects, high price, prolonging ejaculation latency period, etc., and achieve the goal of reducing side effects, reasonable proportioning, and prolonging the sexual life time of men Effect

Inactive Publication Date: 2018-10-09
王大伟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, oral drug therapy is one of the main methods for the treatment of premature ejaculation. Oral drug therapy mainly uses serotonin reuptake inhibitors. Dapoxetine has been marketed in China. It mainly prolongs the ejaculation latency period and has relatively large side effects. and expensive

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] When the patient takes the pharmaceutical composition orally, the unit dosage form is Pagiline 1mg, Paroxetine 10mg, 2 times / day; when a marked effect appears, the frequency of taking the medicine is changed to 1 time / day after continuing to take the medicine for half a month; Pajiline 0.5mg, paroxetine 5mg, 1 time / day; the frequency of taking the medicine was changed to 1 time / the next day in another week, and the medicine was stopped completely in another week. The statistics of the final treatment effect are shown in Table 2:

[0047] Table 2

[0048] .

Embodiment 2

[0050] When the patient takes the pharmaceutical composition orally, the unit dosage form is Pagiline 2mg, Paroxetine 10mg, 2 times / day; when the marked effect appears, the frequency of taking the medicine is changed to 1 time / day after continuing to take the medicine for half a month; Pagiline 1mg, paroxetine 5mg, once a day; the frequency of taking the medicine was changed to once every other day in another week, and the medicine was stopped completely in another week. The statistics of the final treatment effect are shown in Table 3:

[0051] table 3

[0052] .

Embodiment 3

[0054]When the patient takes the pharmaceutical composition orally, the unit dosage form is Pagiline 10mg, Paroxetine 10mg, 2 times / day; when the marked effect appears, the frequency of taking the medicine is changed to 1 time / day after continuing to take the medicine for half a month; Pajiline 5mg, paroxetine 5mg, once a day; the frequency of taking the medicine was changed to once every other day in another week, and the medicine was stopped completely in another week. The statistics of the final treatment effect are shown in Table 4:

[0055] Table 4

[0056] .

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PUM

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Abstract

The invention relates to a pharmaceutical composition, and discloses a pharmaceutical composition used for treating premature ejaculation. The pharmaceutical composition includes pargyline or a pharmaceutical salt of pargyline and paroxetine or a pharmaceutical salt of paroxetine as active components. The weight ratio of the pargyline or the pharmaceutical salt of pargyline to the paroxetine or the pharmaceutical salt of paroxetine is 0.1:10-10:0.1, preferably 1:10-10:1. The pharmaceutical salts are hydrochloride. The pharmaceutical composition also includes optional pharmaceutical adjuvants.The pharmaceutical composition is an oral preparation. A unit dosage form of the oral preparation includes the pargyline of 0.1-10 mg and the pargyline of 0.1-10 mg. A unit dosage form of the oral preparation includes the pargyline of 1-10 mg and the pargyline of 1-10 mg. The pharmaceutical composition has advantages of low medical cost and little side effect.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating premature ejaculation. Background technique [0002] Premature ejaculation is the most common ejaculatory dysfunction, and the incidence rate accounts for more than 1 / 3 of adult men. The clinical manifestation of premature ejaculation is mainly excessive ejaculation. After the man erects, he touches or just touches the vulva of the woman, or for a short time, he ejaculates before reaching orgasm. The causes of premature ejaculation can be divided into psychological premature ejaculation, organic premature ejaculation and premature ejaculation caused by other reasons, among which psychological premature ejaculation is the main cause of premature ejaculation. [0003] At present, oral drug therapy is one of the main methods for the treatment of premature ejaculation. Oral drug therapy mainly uses serotonin reuptake inhibitors. Dapoxetine has...

Claims

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Application Information

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IPC IPC(8): A61K31/4525A61K31/137A61P15/10
CPCA61K31/137A61K31/4525A61K2300/00
Inventor 王大伟
Owner 王大伟