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Application of alpinia officinarum hance diphenylheptane component in preparing preparation for prevention and/or treatment of porcine epidemic diarrhea and preparation

A technology of galangal diphenylheptane and porcine epidemic diarrhea, applied to the preparation of galangal diphenylheptane components in the preparation of prevention and/or treatment of porcine epidemic diarrhea, prevention and/or treatment of porcine epidemic diarrhea In the field of preparations, it can solve problems such as inhibition

Active Publication Date: 2018-10-16
WUHAN NORJAN BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are some feed / feed additives for the treatment of porcine epidemic diarrhea, including multi-flavor compound traditional Chinese medicine, but no further research on the inhibition of PEDV has been carried out

Method used

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  • Application of alpinia officinarum hance diphenylheptane component in preparing preparation for prevention and/or treatment of porcine epidemic diarrhea and preparation
  • Application of alpinia officinarum hance diphenylheptane component in preparing preparation for prevention and/or treatment of porcine epidemic diarrhea and preparation
  • Application of alpinia officinarum hance diphenylheptane component in preparing preparation for prevention and/or treatment of porcine epidemic diarrhea and preparation

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Embodiment 1

[0025] Galanga is extracted with 85% ethanol under reflux, the solvent is recovered until there is no ethanol, suspended in water, extracted with petroleum ether, dichloromethane, and ethyl acetate respectively, and the obtained dichloromethane extraction part is subjected to solvent removal treatment to obtain The diphenylheptane component of galangal is called diphenylheptane S1. Carry out further separation and purification to this diphenylheptane S1, the NMR spectrum of the partially separated and purified diphenylheptane is as follows Figure 2A-9 As shown, it is illustrated that what the above-mentioned treatment obtains is the diphenylheptane components of galanga.

[0026] Wherein, the component of the diphenylheptane of separation and purification comprises:

[0027]

[0028]

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Abstract

The invention belongs to the field of veterinary traditional Chinese medicines, and relates to the application of alpinia officinarum hance diphenylheptane component in preparing a preparation for prevention and / or treatment of porcine epidemic diarrhea (PED) and the preparation. The alpinia officinarum hance diphenylheptane component has a significant anti-PEDV (Porcine Epidemic Diarrhea Virus) activity at concentrations without cytotoxicity, and can be used as the preparation for the prevention and / or treatment of PED.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine for veterinary use, and more specifically relates to the application of galangal diphenylheptane components in the preparation of preparations for preventing and / or treating porcine epidemic diarrhea, and a method for preventing and / or treating porcine epidemic diarrhea. Preparations for diarrhea. Background technique [0002] Porcine epidemic diarrhea (porcine epidemic diarrhea, PED) is an acute, highly contagious intestinal disease of pigs caused by porcine epidemic diarrhea virus (porcine epidemic diarrhea virus, PEDV). PED first occurred in Europe, and it has become very popular in Asia in recent years. In 2010, it broke out in China and brought great harm to the pig industry. PED only occurs in pigs, mostly in winter, and pigs of all ages and breeds are susceptible. The clinical symptoms generally manifest as severe watery diarrhea accompanied by vomiting, obvious dehydration of t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/12A61K31/122A61K31/047A61P1/12A23K20/111A23K50/30
CPCA23K20/111A23K50/30A61K31/047A61K31/12A61K31/122A61P1/12
Inventor 赵玲杨博
Owner WUHAN NORJAN BIOLOGICAL TECH