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Compositions and methods of use of beta-hydroxy-beta-methylbutyrate (HMB) for joint stability

A technology of methylbutyric acid and composition, which is applied in the direction of drug combination, anhydride/acid/halide active ingredients, bone diseases, etc., and can solve problems such as muscle mass and strength increase

Pending Publication Date: 2018-10-23
METABOLIC TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

HMB supplementation is known to lead to increases in muscle mass and strength, and can lead to improved aerobic

Method used

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  • Compositions and methods of use of beta-hydroxy-beta-methylbutyrate (HMB) for joint stability
  • Compositions and methods of use of beta-hydroxy-beta-methylbutyrate (HMB) for joint stability
  • Compositions and methods of use of beta-hydroxy-beta-methylbutyrate (HMB) for joint stability

Examples

Experimental program
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Embodiment Construction

[0033] It was surprisingly and unexpectedly found that HMB improves joint stability, reduces joint stiffness, maintains and / or improves healthy joint function, and improves balance movement. The present invention encompasses HMB compositions and methods of using HMB to reduce joint instability, increase joint stability, reduce joint stiffness, promote healthy joints, increase joint range of motion, improve balance movement, and skeletal joint stability.

[0034] This composition can be used by all age groups seeking these results. The compositions can also be used in humans and non-human mammals, including but not limited to companion animals such as dogs, cats and horses.

[0035] HMB

[0036] β-Hydroxy-β-methylbutyric acid or β-hydroxy-isovaleric acid can be expressed in its free acid form as (CH 3 ) 2 (OH)CCH 2 COOH. The term "HMB" refers to the compound of the foregoing formula and its free acid and salt forms and derivatives thereof. Such derivatives include metabol...

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Abstract

The present invention provides a composition comprising HMB. Methods of administering HMB to an animal are also described. HMB is administered to decrease joint instability, increase joint stability,decrease joint stiffness, improve joint function, improve joint health, improve balanced movement and improve skeletal joint stability during muscle movement. HMB is administered to increase muscle strength and / or muscle mass in a side of the body contralateral to joint inflammation, joint damage, and / or joint injury.

Description

Background of the invention [0001] This application claims priority to US Provisional Patent Application No. 62 / 278,252, filed January 13, 2016, and the provisional application is hereby incorporated by reference. [0002] 1. Domain [0003] The present invention relates to compositions comprising β-hydroxy-β-methylbutyrate (HMB) and methods of using HMB to reduce joint instability, increase joint stability and improve balance movement. [0004] 2. Background [0005] As animals age and their body condition changes, the musculoskeletal system that surrounds joints and provides joint stability may weaken. Joint instability can lead to decreased range of motion and flexibility as well as increased inflammation and pain. The result is decreased activity and the inability to perform everyday tasks such as climbing stairs. [0006] Resistance to joint instability is achieved through healthy tendons, ligaments, fascia and musculature surrounding the joint and can be an import...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/19A61P19/02
CPCA61K31/19A61P19/02
Inventor J·富勒J·拉特马克E·哈里斯S·拜尔
Owner METABOLIC TECH
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