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Vaginal mucosa antibacterial gel and preparation method thereof

A gel and mucous membrane technology, applied in the field of gynecological gel and its preparation, can solve the problems of destroying vaginal acid-base balance and bacterial flora balance, so as to maintain vaginal micro-ecological balance, reduce the number of pathogenic bacteria, improve The effect of vaginal mucosal immunity

Active Publication Date: 2021-05-25
HEILONGJIANG ACAD OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the technical problem of destroying the acid-base balance and flora balance in the vagina while treating inflammation in the existing gynecological gel, and to provide a preparation method of vaginal mucosa antibacterial gel

Method used

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  • Vaginal mucosa antibacterial gel and preparation method thereof
  • Vaginal mucosa antibacterial gel and preparation method thereof
  • Vaginal mucosa antibacterial gel and preparation method thereof

Examples

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Effect test

specific Embodiment approach 1

[0016] Specific embodiment one: In this embodiment, each unit of vaginal mucosa antibacterial gel contains 0.1 g of Sophora japonica extract, 0.2 g of Chinese rose extract, 0.03 g of carbomer, 0.5 g of Tween 80, 1 g of glycerin, and poloxa Mu 188 0.1g and methylparaben added in an amount of 0.1% of the total mass of the vaginal mucosa antibacterial gel.

specific Embodiment approach 2

[0017] Specific embodiment two: the difference between this embodiment and specific embodiment one is that the preparation method of vaginal mucosa antibacterial gel is carried out according to the following steps:

[0018] 1. Weigh 1g of Sophora japonica extract, 2g of Chinese rose extract, 0.3g of carbomer, 5g of Tween 80, 10g of glycerin, and 188.1g of poloxamer;

[0019] 2. Thoroughly grind 1 g of poloxamer 188 and 1 g of Sophora japonica extract to obtain a grinding mixture, mix 10 g of glycerin, 5 g of Tween 80 and 20 ml of purified water, and add the grinding mixture and 2 g of Chinese rose extract, Stir evenly to obtain a suspension;

[0020] 3. Weigh 0.3g of carbomer, add 20g of purified water until it swells completely, and obtain a swelling solution;

[0021] 4. Add the suspension to the swelling solution, and then add 0.1% methyl paraben in an amount equal to the total mass of the vaginal mucosa antibacterial gel to obtain the vaginal mucosa antibacterial gel. Ot...

Embodiment 1

[0024] Embodiment 1: adopt simple Sophora japonica extract (other ingredients are unchanged) to make gel:

[0025] 1. Weigh 1g of Sophora japonica extract, 0.3g of carbomer, 5g of Tween 80, 10g of glycerin, 0.1g of poloxamer 188 and 0.1% of methylparaben.

[0026] 2. Fully grind 1 g of Poloxamer 188 and 1 g of Sophora japonica extract for later use, mix 10 g of glycerin, 5 g of Tween 80 and 20 ml of purified water and stir well, add the grinding mixture to it, and stir evenly to obtain a suspension;

[0027] 3. Weigh 0.3g of carbomer, add 20g of purified water until it swells completely, and obtain a swelling solution;

[0028] 4. Add the suspension to the swelling solution, and then add 0.1% methylparaben to obtain the product.

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Abstract

The vaginal mucosa antibacterial gel and its preparation method relate to a gynecological gel and its preparation method. The invention aims to solve the technical problem that the existing gynecological gel destroys the acid-base balance and flora balance in the vagina while treating inflammation. The antibacterial gel of the present invention contains Sophora japonicus extract, rose flower extract, carbomer, Tween 80, glycerin, poloxamer 188 and methylparaben. Preparation method: 1. Weigh the raw materials; 2. Mix glycerin, Tween 80 and purified water, add Poloxamer 188, Sophora japonica extract and Chinese rose extract; 3. Weigh carbomer 0.3 g, add 20g of purified water until it swells completely to obtain a swelling solution; 4. Add the suspension to the swelling solution, and then add methylparaben to obtain the product. The gel of the present invention maintains the acid-base balance in the vagina while treating female vaginal inflammation, and does not destroy the balance of bacterial flora in the vagina. The gel of the present invention does not destroy the microecology of the vagina while treating it.

Description

technical field [0001] The invention relates to a gynecological gel and a preparation method thereof. Background technique [0002] Vaginitis, or inflammation of the vagina, is a group of conditions that cause vulvovaginal symptoms such as itching, burning, irritation, and abnormal discharge. Due to the characteristics of anatomical tissue, the vagina of normal healthy women has a natural defense function against the invasion of pathogens. For example, the closure of the vaginal opening, the close contact of the front and rear walls of the vagina, the hyperplasia of vaginal epithelial cells and keratinization of surface cells under the influence of estrogen, and the balance of vaginal pH balance inhibits the reproduction of pathogens that adapt to alkaline, while the cervical mucus appears Alkaline, when the natural defense function of the vagina is destroyed, pathogens are easy to invade, leading to vaginal inflammation. Under normal circumstances, there are aerobic bacte...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/738A61K9/06A61P15/00A61P31/02A61P31/04A61P31/10A61P15/02
CPCA61K9/0034A61K9/06A61K36/489A61K36/738A61K47/32A61P15/00A61P15/02A61P31/02A61P31/04A61P31/10A61K2300/00
Inventor 王伟明霍金海李梦雪刘华石潘五九韩德强
Owner HEILONGJIANG ACAD OF TCM
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