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Application of polygonum divaricatum, polygonum tortuosum and polygonum polystachyum total extractive, as well as elution positions thereof for preparing medicine for treating ulcerative colitis

A kind of technology of ulcerative colitis and Polygonum fork, applied in the field of traditional Chinese medicine preparation

Inactive Publication Date: 2019-01-01
JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Method used

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  • Application of polygonum divaricatum, polygonum tortuosum and polygonum polystachyum total extractive, as well as elution positions thereof for preparing medicine for treating ulcerative colitis
  • Application of polygonum divaricatum, polygonum tortuosum and polygonum polystachyum total extractive, as well as elution positions thereof for preparing medicine for treating ulcerative colitis
  • Application of polygonum divaricatum, polygonum tortuosum and polygonum polystachyum total extractive, as well as elution positions thereof for preparing medicine for treating ulcerative colitis

Examples

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Comparison scheme
Effect test

Embodiment 1

[0019] The preparation method of the total extract of Polygonum bifurcis, wherein: pulverize the medicinal material of Polygonum bifurcates into coarse powder, soak in water for 1 hour, heat and decoct 8 times the amount of water to extract 3 times, each time for 2 hours, filter, and combine the filtrates. The above filtrate was concentrated under reduced pressure to obtain the total water extract.

Embodiment 2

[0021] The preparation method of the total extract of Polygonum formosanus, wherein: the medicinal material of Polygonum formosanus is crushed into coarse powder, soaked in water for 1 hour, heated and decocted with 8 times the amount of water for extraction for 3 times, each time for 2 hours, filtered, and the filtrates are combined. The above filtrate was concentrated under reduced pressure to obtain the total water extract.

Embodiment 3

[0023] The preparation method of the Polygonum multispike total extract, wherein: the Polygonum multispike medicinal material is crushed into a coarse powder, soaked in water for 1 hour, heated and decocted in 8 times the amount of water to extract 3 times, each time for 2 hours, filtered, and the filtrates are combined. The above filtrate was concentrated under reduced pressure to obtain the total water extract.

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Abstract

The invention relates to application of polygonum divaricatum, polygonum tortuosum and polygonum polystachyum total extractive, as well as elution positions thereof for preparing medicine for treatingulcerative colitis. The prepared polygonum divaricatum, polygonum tortuosum and polygonum polystachyum total extractive is ethyl alcohol aqueous extraction concentration total extractive of polygonumdivaricatum, or polygonum tortuosum or polygonum polystachyum, wherein the ethyl alcohol aqueous extraction concentration total extractive have different concentrations of 0-100%. The elution positions of the prepared polygonum divaricatum, polygonum tortuosum and polygonum polystachyum is characterized in that the ethyl alcohol aqueous extraction concentration total extractive with different concentrations of 0-100% of polygonum divaricatum, or polygonum tortuosum or polygonum polystachyum is eluted by water, 35% ethyl alcohol water, 70% ethyl alcohol water and 95% ethyl alcohol water afterbeing processed by macroporous adsorption resin to obtain a water elution position, 35% ethyl alcohol water elution position, 70% ethyl alcohol water elution position and 95% ethyl alcohol water elution position. The above elution positions of the polygonum divaricatum or polygonum tortuosum or polygonum polystachyum is used for preparing the medicine for treating ulcerative colitis.

Description

technical field [0001] The present invention relates to the application of the total extracts of Polygonum formosanus, Polygonum formosanus and Polygonum multispike and the elution parts thereof in the preparation of medicines for treating ulcerative colitis, and belongs to the technical field of traditional Chinese medicine preparation. Background technique [0002] Polygonum divaricatum is the dried root or whole herb of Polygonum divaricatum L. in the genus Polygonaceae (Polygonaceae) used as medicine. The medicine tastes sour, bitter, and astringent, and its nature is cool, dilute, light, astringent, and blunt. It has the effects of clearing heat, stopping diarrhea, and stopping bleeding. It is mainly used to treat intestinal tingling, less frequent stools, bloody stools, mixed with mucus, and tenesmus. [0003] Polygonum polystachyum is the dried root or whole herb of Polygonum polystachyum Wall. ex Meisn. in the family Polygonaceae (Polygonaceae). It has the effects ...

Claims

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Application Information

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IPC IPC(8): A61K36/704A61P1/00A61P1/04
CPCA61K36/704A61K2236/333A61K2236/39A61K2236/55A61P1/00A61P1/04
Inventor 董丽华张忠立朱玉野左月明罗光明钟国跃
Owner JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE