A kind of phosphorus adsorbent and its preparation method and application

The technology of a phosphorus adsorbent and a cross-linking agent is applied in the field of phosphorus adsorbent and its preparation, which can solve the problems of easily causing side reactions and high toxicity, and achieves the effects of being suitable for popularization and application, high phosphorus adsorption capacity, and reducing blood phosphorus level.
CN109126741BActive Publication Date: 2021-04-30HEBEI UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HEBEI UNIVERSITY
Publication Date
2021-04-30

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Abstract

The invention provides a phosphorus adsorbent and its preparation method and application. The phosphorus adsorbent has the following structure: wherein, X is a natural high-molecular organic substance containing a hydroxyl group. The phosphorus adsorbent is prepared by grafting polyallylamine on the natural macromolecular organic matter under the initiation system; or, by grafting polyacrylamide on the natural high molecular organic matter under the initiation system, and then passing Hoffman produced by degradation. The initiating system is one of redox agent initiating, photoinitiator initiating, microwave initiating, radiation initiating or thermal initiating. The phosphorus adsorbent of the invention has high phosphorus adsorption capacity, can significantly reduce the blood phosphorus level, has no side reaction, has high safety and good curative effect, is suitable for popularization and application, and has broad market prospects.
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Description

technical field

[0001] The invention relates to the technical field of oral phosphorus adsorbents, in particular to a phosphorus adsorbent and its preparation method and application. Background technique

[0002] Phosphorus widely exists in nature and is one of the necessary elements in animal and plant tissues. Phosphorus is abundant in the human body, and its metabolic process is closely related to human health. For example, the failure of renal function in patients with end-stage renal disease (ESRD) leads to difficulty in excreting phosphorus, which increases the accumulation of phosphorus in the body and induces hyperphosphatemia. Elevated blood phosphorus levels stimulate increased parathyroid secretion, leading to secondary hyperparathyroidism. Hyperparathyroidism will induce renal bone disease, causing bone tissue to release a large amount of phosphorus, aggravating hyperphosphatemia, and causing a vicious circle. Clinical reports show that most patients with end-...

Claims

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