Ginkgo leaf drop pill and preparation method thereof

A technology of leaf drop pills and ginkgo leaf, which is applied in the field of ginkgo leaf drop pills and its preparation, can solve the problems of ginkgo leaf drop pills with poor blood lipid regulation effect and low bioavailability, and achieve obvious blood lipid lowering effect, good effect, and obvious The effect of economic benefits

Inactive Publication Date: 2019-01-18
华玉海
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is: the Ginkgo biloba dripping pi

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0031] The invention also provides a preparation method of the ginkgo biloba dripping pill, which comprises the following steps:

[0032] a. Take dried ginkgo leaves, add 6-7 times the volume of 50-60% ethanol solution, then add sodium bicarbonate to adjust the pH to 8.5-10.5, place it in an ultrasonic container, extract for 10-20min, use Biofilm filtration, collecting the first filtrate;

[0033] Add the filtered ginkgo biloba leaves to 6-7 times the volume of 70-80% ethanol solution, then add sodium bicarbonate to adjust the pH to 8.5-10.5, place it in an ultrasonic container, extract for 20-30min, use biological Membrane filtration, collect the second filtrate;

[0034] Add the ginkgo biloba leaves obtained by the second filtration to 6-7 times the volume of a 50-60% ethanol solution, then add sodium bicarbonate to adjust the pH to 8.5-10.5, place in an ultrasonic container, and extract for 10-20 minutes , Use biomembrane filtration to collect the third filtrate;

[0035] Combine...

Example Embodiment

[0044] Example 1 Preparation of ginkgo biloba dripping pills by the method of the present invention

[0045] The composition of Ginkgo Leaf Dropping Pills includes: in parts by weight, 50 parts of Ginkgo biloba leaves, 20 parts of Danshen extract, 10 parts of grape seed oil, 20 parts of tartary buckwheat powder, and 20 parts of golden locust leaf extract.

[0046] The preparation method of ginkgo leaf dripping pills is as follows:

[0047] a. Take dried ginkgo leaves, add 6 times the volume of 50% ethanol solution, add sodium bicarbonate to adjust the pH to 8.5, place in an ultrasonic container, extract for 10min, filter by biofilm, collect the first time The filtrate;

[0048] Add the filtered ginkgo biloba leaves to 6 times the volume of 70% ethanol solution, then add sodium bicarbonate to adjust the pH to 8.5, place in an ultrasonic container, extract for 20min, filter by biofilm, collect the second filtrate;

[0049] The ginkgo biloba leaves obtained from the second filtration wer...

Example Embodiment

[0054] Example 2 Preparation of ginkgo biloba dripping pills by the method of the present invention

[0055] The composition of Ginkgo Leaf Dropping Pills includes: 70 parts of Ginkgo biloba leaves, 10 parts of Salvia miltiorrhiza extract, 5 parts of grape seed oil, 10 parts of tartary buckwheat powder, and 10 parts of golden locust leaf extract in parts by weight.

[0056] The preparation method of ginkgo leaf dripping pills is as follows:

[0057] a. Take the dried ginkgo leaves, add 7 times the volume of the ethanol solution with a mass concentration of 60%, then add sodium bicarbonate to adjust the pH to 10.5, place it in an ultrasonic container, extract for 20 minutes, use biofilm filtration, and collect the first time The filtrate;

[0058] Add the filtered ginkgo biloba leaves to 7 times the volume of 80% ethanol solution, then add sodium bicarbonate to adjust the pH to 10.5, place it in an ultrasonic container, extract for 30min, use biofilm filtration, collect the second time...

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Abstract

The invention belongs to the field of traditional Chinese medicine preparation, in particular to a ginkgo leaf drop pill and a preparation method thereof. The invention provides a ginkgo leaf drop pill for reducing blood lipid and a preparation method thereof, aiming at the problems of poor blood lipid regulating effect and low bioavailability of the ginkgo leaf drop pill prepared by the prior method. The preparation method of ginkgo dripping pills comprises the following steps: a, taking dried leaves of ginkgo, adding into ethanol solution, adopting ultrasonic extraction, adopting biofilm filtration, and extracting at least three times; mixing the collected filtrates, concentrating to obtain concentrated solution, and drying to obtain extract; ginkgo leaf drop pill is prepared by adding radix Salviae Miltiorrhizae extract, grape seed oil, tartary buckwheat powder and folium Sophorae Japonicae extract, matrix and p-aminobenzoic acid. As that method of the invention is use together withthe ultrasonic extraction and the biological membrane filtration, the extraction rate of the ginkgo biloba leaves can be improve, a special substrate is selected when preparing the dripping pill, andp-aminobenzoic acid is added, the drug dissolution rate is 10 times faster than that of the traditional method, and the economic benefit is remarkable.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a ginkgo leaf dripping pill and a preparation method thereof. Background technique [0002] Ginkgo biloba is the leaf of Ginkgo biloba, a plant of the genus Ginkgo. It contains flavonoids, terpenes, phenols, beneficial trace elements and 17 amino acids and other active ingredients. It has the functions of lowering serum cholesterol, increasing coronary blood flow, improving cerebral blood circulation, and Smooth muscle spasm, bronchial relaxation and pharmacological effects such as antibacterial. Clinically, it is not only used to treat cardiovascular and cerebrovascular diseases, but also has good effects on the nervous system and respiratory system. [0003] Although there are many active ingredients in Ginkgo biloba, the ginkgolic acid in it is a toxic ingredient. Therefore, Ginkgo biloba cannot be directly used for pharmaceuticals. Special...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61K9/20A61K47/18A61K47/36A61P3/06A61P39/06
CPCA61K36/16A61K9/2013A61K9/205A61K36/53A61K36/537A61K36/70A61K36/87A61K2236/333A61K2236/39A61K2236/53A61P3/06A61P39/06A61K2300/00
Inventor 华玉海
Owner 华玉海
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