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Preparation method of anti-yellowing silver-containing dressing

A silver dressing and anti-yellowing technology, which is applied in the field of preparation of anti-yellowing silver-containing dressings, can solve problems such as blackening, yellowing, and affecting the use of dressings, so as to prevent exudate from seeping back, and increase adsorption speed and adsorption capacity , to avoid the effect of wound adhesion

Inactive Publication Date: 2019-01-29
苏州汇涵医用科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the oxidative properties of silver, silver-loaded dressings such as gauze, bandages, etc. will turn yellow or even black under high temperature, light or long-term storage and transportation, which will affect the use of dressings.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A) Silver ion carrier modification, the gauze as silver ion carrier is treated to improve adhesion, specifically adopts the corona treatment method to utilize high frequency and high voltage to corona discharge on the gauze surface, and the process parameters of corona discharge are: frequency It is adapted to 20 kHz, the output power is 2.5 kW, and the traveling speed of the gauze is 5 m / min. The low-temperature plasma generated by the corona discharge causes the free radical reaction on the surface of the gauze, thereby obtaining a modified silver ion carrier, that is, an improved sexual gauze;

[0023] B) Preparation of silver ion solution containing anti-yellowing agent, the mass % specific concentration (final concentration) of 5% polyvinylpyrrolidone is added to the silver nitrate solution with a concentration of 10ppm and stirred to obtain polyvinylpyrrolidone containing silver ion solution;

[0024] C) dipping, the modified gauze obtained by step A) is dropped ...

Embodiment 2

[0027] A) Silver ion carrier modification, the non-woven fabric as a silver ion carrier is treated to improve adhesion, specifically, the corona treatment method is used to corona discharge and corona discharge on the surface of the non-woven fabric with high frequency and high voltage. Parameters are the same as in Example 1, low-temperature plasma is generated by corona discharge to cause free radical reaction on the surface of the non-woven fabric, thereby obtaining a modified silver ion carrier, that is, a modified non-woven fabric;

[0028] B) preparation contains the silver ion solution of anti-yellowing agent, the polyacrylic acid and the polymethacrylic acid that are 0.1% are joined in the silver nitrate solution that concentration is 500ppm by mass % specific concentration (final concentration) and stir well, obtain containing polyacrylic acid Silver ion solutions of acrylic acid and polymethacrylic acid;

[0029] C) Impregnation, put the modified non-woven fabric obt...

Embodiment 3

[0032] A) silver ion carrier modification, the absorbent cotton as silver ion carrier is treated to improve adhesion, specifically the corona treatment method is used to use high frequency and high voltage to corona discharge on the surface of absorbent cotton, and the process parameters of corona discharge are: frequency It is adapted to 20kHz, the output power is 3.5 kW, and the traveling speed of the absorbent cotton is 5 m / min. The low-temperature plasma is generated by the corona discharge to cause free radical reactions on the surface of the absorbent cotton, thereby obtaining a modified silver ion carrier, that is, a modified silver ion carrier. absorbent cotton;

[0033] B) preparation contains the silver ion solution of anti-yellowing agent, is that chitosan, polyethylene glycol and sodium alginate of 1.7% are joined in the silver sulfadiazine solution that concentration is 165ppm by mass % ratio concentration (final concentration) and Stir well to obtain a silver ion...

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PUM

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Abstract

The invention relates to a preparation method of anti-yellowing silver-containing dressing, and belongs to the technical field of medical dressing preparation. The method comprises the following stepsof performing adhesion performance improving treatment on a silver ion carrier to obtain a modified silver ion carrier; adding anti-yellowing agents with the mass percentage ratio concentration being0.1 to 5 percent into a silver ion solution with the concentration being 10 to 500ppm; performing uniform stirring; obtaining the silver ion solution containing an anti-yellowing agent; putting the obtained modified silver ion carrier into the obtained silver ion solution containing the anti-yellowing agent to be soaked; after the soaking completion, taking out the carrier; draining the carrier so as to obtain a silver-ion-containing carrier adsorbed with the silver ions; firstly exerting a pregel solution onto the surface of the obtained silver-ion-containing carrier adsorbed with the silverions; then, performing curing and shaping; and finally performing cutting and packaging to obtain the anti-yellowing silver-containing dressing. The adsorption speed of the silver ion carrier on polar substances is accelerated; the adsorption capability of the silver ion carrier on the polar substance is improved; the yellowing or even blackening of the anti-yellowing silver-containing dressing can be avoided; the moist state of the wound is maintained; the wound conglutination is avoided; and the backward seepage of exudate is prevented.

Description

technical field [0001] The invention belongs to the technical field of preparation of medical dressings, and in particular relates to a preparation method of an anti-yellowing silver-containing dressing. Background technique [0002] Traditional dressings represented by gauze, bandages, etc. are still the most widely used nursing materials in clinical wound care. Their porous fiber structure not only maintains good air permeability of the wound, but also makes the wound easy to be infected by various bacteria. Nursing is a key factor affecting wound healing, so how to control wound infection is a very important topic in the field of wound care. [0003] Silver is a broad-spectrum antibacterial agent. Compared with antibiotics and other bacteriostatic drugs commonly used in clinical practice, silver can effectively kill and inhibit pathogenic microorganisms on various wounds without tolerance, and the antibacterial time is long. Therefore, It is widely used in wound care of ...

Claims

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Application Information

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IPC IPC(8): A61L15/44A61L15/18A61L15/42A61L15/24A61L15/28A61L15/26
CPCA61L15/18A61L15/24A61L15/26A61L15/28A61L15/42A61L15/425A61L15/44A61L2300/104A61L2300/404A61L2400/00C08L39/06C08L33/02C08L5/08C08L71/02C08L5/04
Inventor 古元安李冲冯永良
Owner 苏州汇涵医用科技发展有限公司
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