55results about How to "Keep the wound moist" patented technology

The invention relates to an antibacterial heal-promoting gel material used for preparing medical wound dressing and a preparation method thereof. The antibacterial heal-promoting gel material used for preparing the medical wound dressing is characterized in that the antibacterial heal-promoting gel material comprises natural gel agents, chitosan, bioactive materials, soluble silver salt and organic acids, water is added into the ingredients, the water content accounts for 5 to 20 times of the weight sum of the natural gel agents and the chitosan, and then, the antibacterial heal-promoting gelmaterial of any forms can be obtained through cross-linked curing and aftertreatment. The antibacterial heal-promoting gel material is metered according to dry basis, and is prepared form the following ingredients in percentage by weight:57 to 90.9 percent of natural gel agents, 5 to 25 percent of bioactive materials, 2 to 8 percent of chitosan, 0.1 to 2 of soluble silver salt and 2 to 8 percent of organic acids. The antibacterial heal-promoting gel material has good biocompatibility, good antibiotic property, strong tissue regeneration promoting capacity and various forms, and can be easily and conveniently prepared into the medical wound dressing.

The invention discloses a composition for nursing skin wounds. The composition comprises the following components: montmorillonite, mycose and sodium alga acid according to the mass ratio of (20-50) to (5-20) to (20-50). The composition for nursing skin wounds disclosed by the invention can be used for carrying out broad-spectrum antisepsis, effectively killing bacteria, preventing wound infection, effectively keeping the wound humidity, accelerating wound healing, effectively inhibiting scar formation after wound healing, and absorbing excessive effusion and wound odors, and keeping the wounds fresh and cool.

A dual-layer scaffold for the skin regeneration is composed of a porous collagen-chitosan scaffold for inducing the migration, reproduction and differentiation of cells and the generation of dermal tissue and a silica rubber film as temporary epidermal layer for preventing the volatilization of water and the intrusion of bacteria. It has high biocompatibility, controllable degradation speed and excellent wound repairing power.

The invention provides a glucan-based transparent hydrogel dressing and a preparation method thereof. The preparation method of the glucan-based transparent hydrogel dressing comprises the following steps: conducting a reaction between a glucan quaternary ammonium salt derivative and succinic anhydride; then promoting an obtained product to react with small molecules of amination, so that a macromonomer which contains illuminated cross-linking double bonds is obtained; mixing the macromonomer which contains illuminated cross-linking double bonds with an antibacterial agent and an initiating agent; conducting photo initiation so as to prepare a glucan-based transparent hydrogel; and combining the glucan-based transparent hydrogel with a polyurethane film by virtue of a bonding agent, so that the glucan-based transparent hydrogel dressing is prepared. The finished product (the glucan-based transparent hydrogel dressing) prepared by the invention not only can absorb a great amount of wound exudates so as to keep a wound surface wet, but also can avoid wound adhesion, so that the probability of wound infection is reduced and wound surface healing is promoted.

The invention discloses an injectable self-repairing antibacterial hydrogel dressing of preloaded polypeptide and a preparation method thereof. The hydrogel dressing includes hydrogel combined with fabric, and polypeptides promoting fibroblast migration are distributed on the surface and inside of the hydrogel. The preparation method is as follows: dextran with different molecular weights is selectively oxidized by an oxidant to form an aldylated dextran; a partially alkylated dextran is obtained by reacting an aldylated dextran with aliphatic amine; and then the polypeptide is prepared in a solid phase ; Formaldehyde dextran, adipate dihydrazide and partially alkylated dextran were dissolved in PBS buffer respectively, and the polypeptide was added to the formaldehyde dextran solution, pre-loaded with solid-phase synthesized For the polypeptide, the three solutions are mixed according to a certain mass ratio to prepare an injectable self-repairing antibacterial hydrogel of the preloaded polypeptide, which is finally made into a dressing. The product prepared by the invention has good antibacterial performance, can reduce the chance of wound infection, and its dynamic self-repair performance can target irregular wounds, and can also keep the wound surface moist and accelerate wound healing.