The invention discloses a food-grade antibacterial freshness protection plastic packing bag. The food-grade antibacterial freshness protection plastic packing bag is prepared from the following raw materials in parts by weight: 60-70 parts of polyethylene masterbatches, 10-15 parts of propylene-butene-1 random copolymer, 15-20 parts of pueraria starch, 5-8 parts of reed fibers, 6-12 parts of nano-bentonite, 1-3 parts of a radical initiator, 2-4 parts of propolis, 2-6 parts of phytic acid, 0.5-1 part of orange peel essential oil, 0.3-0.5 part of citronella oil, 0.3-0.5 parts of thyme essentialoil, 8-10 parts of chitosan, 5-7 parts of a pH regulator, 5-7 parts of tea polyphenols, 4-6 parts of graphene, 1-3 parts of a preservative and 1-3 parts of an epoxy silane coupling agent. The propolis, the phytic acid, the orange peel essential oil, the citronella oil, the thyme essential oil, the chitosan and the tea polyphenols are added in the raw materials, the food-grade antibacterial freshness protection plastic packing bag has an antibacterial property and anti-corrosion property, breeding of bacteria in the bag is inhibited effectively, corrosion is prevented, and freshness of food andusing safety can be ensured effectively.