8results about How to "Activate the immune system" patented technology

The invention relates to a broad-spectrum bacteriostatic lactic acid bacteria postbiotic preparation, a preparation method and application to laying hens, the lactic acid bacteria postbiotic preparation comprises lactic acid bacteria thalli and fermentation products of the lactic acid bacteria thalli, and lactic acid bacteria comprise lactobacillus plantarum LP45 and bifidobacterium animalis BAL531. The feed additive is prepared from lactobacillus plantarum LP45 and bifidobacterium animalis BAL531 through mixed fermentation and low-temperature vacuum drying, pathogenic bacteria such as clostridium perfringens, escherichia coli and salmonella can be inhibited, the abundance of beneficial bacteria in the intestinal tracts of chicken flocks is improved, the state of excrement is improved, chicken necrotic enteritis and diarrhea are prevented and treated, the intestinal health of laying hens is improved, and the laying hens are prevented and cured. The digestion and absorption efficiency of the feed is improved, and the laying rate is increased.

The invention provides a preparation method and application of a TEMP (Tetraethyl Methacrylate) Lip nano material, and the preparation materials of the TEMP Lip nano material comprise CH3CH2OH, CHCl3, THF (tetrahydrofuran), CH2Cl2, N (CH3) 3, NHS (N-Hydroxysuccinimide), 3-mercaptopropionic acid, 1, 3-dicyclohexylcarbodiimide, 4-amino-2, 2, 6, 6-tetramethylpiperidine, PBS (Phosphate Buffer Solution), alpha-GalCer, (2, 3-dioleoxy propyl) trimethyl ammonium chloride (DOTAP), 1, 2-dioleoyl-SN-glycerol-3-phosphorylethanolamine and dioleoyl phosphatidyl ethanolamine. The TEMP (at) Lip nano material is small in particle size and uniform in distribution, has negative potential, is good in corresponding biological solubility, is relatively stable in property after entering a living body, can safely transport an iNKT cell agonist, activates iNKT to improve the autoimmunity of the living body, and realizes the aim of treating tumors by using an autoimmune system.

The application discloses application of an immune elicitor protein FvXynC and a protein combination in plant disease resistance, and belongs to the technical field of plant immune elicitors. A new immune elicitor protein FvXynC is found from F. pseudograminearum, and the immune elicitor protein has the core functions of activating plant immune response and improving plant resistance to F. pseudograminearum, can be used as an efficient plant immune inducer, provides a new technical path for plant disease resistance improvement and green plant disease control, and has important agricultural application value. The FvXynC and the immune elicitor protein FvGH43A are compounded, so that the resistance level of corn to F. pseudograminearum can be synergistically improved, and the problem that the plant disease control effect of a single immune elicitor protein is limited is solved.

This invention discloses a bismuth-copper bimetallic coordination nanomaterial, its preparation method, and its applications, belonging to the technical field of biofunctional materials. The prepared bismuth-copper bimetallic coordination nanomaterial can efficiently generate reactive oxygen species (ROS) under ultrasonic stimulation, initiating the sonodynamic therapy (SDT) process; the Cu in this material... 2+ The weakly acidic environment of the tumor microenvironment can also trigger a Fenton-like reaction, generating cytotoxic hydroxyl radicals (•OH) and oxygen in situ, thus initiating the chemokinetic therapy (CDT) process. Through the synergistic effect of sonodynamic therapy (SDT) and chemokinetic therapy (CDT), they jointly inhibit cancer cell proliferation and promote T cell generation.

The present application relates to the technical field of soilless cultivation, and specifically discloses a vegetable soilless cultivation seedling and a seedling raising method thereof. The seedling raising method of the vegetable soilless cultivation seedling comprises the following steps: cleaning and disinfecting the vegetable seeds, soaking the vegetable seeds in a soaking liquid, dark treatment, planting in a soilless cultivation matrix, and obtaining vegetable seedlings. The soilless cultivation matrix includes a solid matrix and a liquid matrix, wherein the solid matrix includes modified rock wool, modified perlite and gravel, and the liquid matrix includes vegetable crop tail vegetables, a fermentation agent, brown sugar, a pH regulator, and a heavy metal ion chelator. The vegetable soilless cultivation matrix prepared in the present application has good water retention, has a certain preventive and therapeutic effect on pests and diseases, and can solve the problem of heavy metal pollution in seedling raising. The seedling raising method used in the present application has a high germination rate of vegetable seeds, strong resistance to pests and diseases, and a good growth state.

Provided are a tumor immunotherapy polypeptide and its application. The polypeptide includes at least one polypeptide in the first peptide group, and may also selectively include at least one polypeptide in the second peptide group; the first peptide group includes a polypeptide having an amino acid sequence shown in SEQ ID NO: 1 to SEQ ID NO: 6 and a first derivative peptide; the second peptide group includes a polypeptide having an amino acid sequence shown in SEQ ID NO: 7 to SEQ ID NO: 15 and a second derivative peptide. Also provided are isolated nucleic acids, constructs, expression vectors, host cells, pharmaceutical compositions, antigen presenting cells, immune effector cells, tumor vaccines, and uses of the polypeptide in preparing drugs for preventing or treating tumors and methods for treating tumor patients.

The present invention proposes a mattress material based on natural mineral crystals and a preparation method thereof, and belongs to the technical field of crystal materials. A porous photocatalytic crystal material is prepared by sol-gel reaction, magnetic ferrosoferric oxide is deposited on the surface, modified by a silane coupling agent, copper oxide, manganese oxide and rare earth oxide are attached, calcined, added to chitosan-gelatin hydrogel, acrylamide is added, an initiator and a cross-linking agent are added, heated and stirred to react, and light-cured to obtain a mattress material based on natural mineral crystals. The mattress material based on natural mineral crystals prepared by the present invention has low cost, can adjust sleeping body temperature and humidity, has good comfort, good antibacterial, anti-insect and anti-mite properties, good durability, emits far-infrared waves and generates magnetic fields, generates negative ions to improve human health, purifies environmental gases, and is deeply loved by consumers.

The invention provides an application of a short peptide MP41 and a protein MLC1 of a gray leaf hopper elicitor in improving the insect resistance of a plant and an insect resistance method, and belongs to the field of bioengineering. The gray leaf hopper elicitor protein MLC1 and the short peptide MP41 can obviously activate the plant immune system, provide the insect resistance of the plant, and effectively prevent or reduce the occurrence of insect pests; they provide a new way to improve the insect resistance of the plant, and provide resources for the development and application of biological pesticides in the future. They can be used as a new type of protein pesticide to defend against the invasion of insect pests, and also provide a basis for the future transgenic plants of the gene, and have broad application prospects in agricultural production.