Heterogeneous dual nanoparticle structure insensitive to polarization state of excitation light and application thereof

Abstract

The invention discloses a heterogeneous dual nanoparticle structure insensitive to polarization state of excitation light and an application thereof, belonging to the technical field of molecular identification and nano-probes in life science. The heterogeneous dual nanoparticle structure is formed based on a core-capped nanoparticle which breaks spherical symmetry and a nanoparticle structure with spherical symmetry. The missing optical properties of an original single core-capped nanoparticle is compensated by using the surface plasmon resonance coupling effect generated between the two nanoparticles when the polarization state of the excitation light is parallel to the symmetry axis of the original single core-capped nanoparticle, so that the dependence relation between the extinction property of the nanoparticles of the core cap structure and the dual nanoparticle structure on the polarization direction of the excitation light is removed. The heterogeneous dual nanoparticle structure can be used as a molecular probe for the molecular recognition with high specificity, and is especially suitable for simultaneous automatic matching of the polarization states of multiple dual nanoparticle structure targets with spatial random pose.

Description

technical field [0001] The invention belongs to the technical field of molecular recognition and nanoprobes in life sciences, and in particular relates to a heterogeneous double nanoparticle structure insensitive to the polarization state of excitation light and its application. Background technique [0002] Noble metal nanoparticles such as gold, silver, and platinum have localized surface plasmon resonance (LSPR), and exhibit unique optical properties in the visible to near-infrared bands. It has important application value in biomedical related fields such as scattering and photothermal diagnosis and treatment. The LSPR peak absorption wavelength of these noble metal nanoparticles strongly depends on their own structural parameters, such as size, shape, particle distance, and dielectric constant of the environment, etc. By adjusting the structural parameters, the movement of the LSPR wavelength can be artificially controlled. The 700nm-1200nm near-infrared band can effec...

AI Technical Summary

Problems solved by technology

However, in practical applications, since each nanoparticle is in any random attitude in space, it is necessary to rotate the polarization direction of the incident light to match the attitude of the particle. In the case of multiple targets, such matching becomes more time-consuming And troublesome, because the polarization direction of the incident light is difficult to match every particle at the same time, so fine polarization state rotation scanning and subsequent algorithm design are required to achieve the matching of each attitude target and accurate target information extraction

For this reason, how to automatically match each posture at the same time, and at the same time obtain and utilize the optical properties of these core-cap noble metal nanoparticles is highly anticipated, but the corresponding methods are rarely reported.

Images