Sterilization method for connection equipment of isolator and dryer and seal ring

Abstract

The invention relates to a sterilization method for connection equipment of an isolator and a dryer and a seal ring. The sterilization method includes steps: closing a seal door between the isolator and the dryer, subjecting the dryer to high-temperature sterilization, and allowing high-temperature steam to sterilize the seal ring through an air inlet of the seal ring on the seal door; after sterilization of the dryer and the seal ring is finished, inflating the seal ring through the air inlet of the seal ring to make the seal ring fit a seal door body; sterilizing the isolator. By the sterilization method, the problem and risk of failure in effective sterilization of the seal ring on the automatic seal door between the isolator and the dryer can be solved, high-temperature gas for sterilization of the seal ring is provided by a high-temperature air source in the dryer, extra high-temperature air sources are avoided, and accordingly sterilization cost is further reduced.

Description

technical field [0001] The present invention relates to the technical field of sterilization, and more particularly, to a sterilization method and a sealing ring for connecting equipment between an isolator and a dryer. Background technique [0002] With the continuous development of the pharmaceutical industry, many pharmaceutical companies or pharmaceutical equipment companies continue to improve their own technology. Among them, the sterile environment has a profound impact on the products or equipment of pharmaceutical companies. At present, the internal environment of the isolator and the dryer can reach a sterile environment, but the connecting equipment (automatic sealing door) between the two has a sterilization dead angle. The flow dead zone is long, resulting in limited heat convection and conduction to the sealing ring position. In addition, the thermal conductivity of the sealing ring rubber material on the automatic sealing door is worse than that of stainless ...

AI Technical Summary

Problems solved by technology

At present, the internal environment of the isolator and the dryer can reach a sterile environment, but the connecting equipment (automatic sealing door) between the two has a sterilization dead angle. The flow dead zone is long, resulting in limited heat convection and conduction to the sealing ring position. In addition, the thermal conductivity of the sealing ring rubber material on the automatic sealing door is worse than that of stainless steel, so the sterilization temperature point of the sealing ring itself is difficult to meet the requirements. value; when the isolator is sterilized with hydrogen peroxide, the airtight door is closed, which also leads to the failure of effective sterilization of the sealing ring, so the incomplete sterilization of the sealing ring itself leads to the risk of contamination during the production of the medicine bottle

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