System and method for detecting and amplifying intracranial cerebral electrophysiological signals

Abstract

The invention discloses a system and method for detecting and amplifying intracranial cerebral electrophysiological signals, wherein the system includes a multi-channel electrode probe sensor, a multi-channel selector, an amplifier, a gated frequency regulator, a zero-setting resistor and an analog-to-digital conversion system. A pad PAD of the multi-channel electrode probe sensor is connected tothe input end of the amplifier through a multiplexer; the other end of the multiplexer is connected to the gated frequency regulator; the input end of the amplifier is connected to the earth through the zero-setting resistor; the amplifier is an integrated second-order bandpass filter consisting of two stand-alone amplifier cores in two-stage cascading, one of two low noise amplifiers is a low-pass filter, and the other one is a high-pass filter; the output end of the amplifier is connected to an analog-to-digital converter.

Description

technical field [0001] The present disclosure relates to the technical field of bioelectricity processing, in particular to a system and method for detecting and amplifying intracranial brain electrophysiological signals. Background technique [0002] The correct extraction of intracranial EEG signals is of great significance for the diagnosis and analysis of deep-seated intracranial brain diseases, and for the construction of micro-implanted sensing detection systems in the future. However, most of the current inventions use purchased chips to build intracranial EEG acquisition systems, and do not provide specific probes and circuit structures for unified sensors and weak biological signals cascaded behind. For future implantable EEG collection chip systems, the present disclosure has important practical application value. [0003] The patent "Electrode System for Deep Brain Stimulation" of Royal Philips Electronics Co., Ltd. with the Chinese published application number "...

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Problems solved by technology

[0006] China's published application number is "201621240371.8", the patent of "EEG Signal Acquisition System" of the Ministry of Industry and Information Technology Research Institute of Telecommunications. This patent discloses an EEG signal acquisition system for collecting the responses of animals and plants to electromagnetic radiation. The system includes EEG amplifier, electromagnetic pulse irradiation source, and microwave anechoic chamber. Then, the inventor realized that the patent described a general EEG acquisition system, but it did not have the integrated circuit of the amplifier dedicated to the intracranial EEG sensor proposed in this disclosure structure

[0007] The patent of "Portable Low-Power High-Performance EEG Amplifier Circuit" issued by Zhongyuan Institute of Electronic Technology with the Chinese Public Application No. "201420757563.0" discloses a small, portable, low-energy consumption, high-performance extracranial EEG EEG amplifier circuit, which includes a preprocessing circuit, an integrated analog front end, a signal processing and control module, and a WIFI module. Then, the inventor realized that this patent does not have the high integration of the EEG amplification chip proposed in this disclosure, nor does it give Output amplifier internal circuit structure

[0008] The patent "A Bioelectrical Signal Amplifier" of Henan Agricultural University with the Chinese published application number "201320137657.3" describes the general composition of EEG amplification, but it does not have the EEG amplification application-specific integrated circuit proposed in this disclosure Highly integrated features, and no specific circuit structure is given

[0009] In summary, in the prior art, the specific circuit architecture of the intracranial EEG amplifier and the internal structure of the corresponding circuit are not given.

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