A high-precision ultra-high pressure liquid phase simulation load accumulation error test platform

Abstract

The invention discloses a high-precision ultrahigh-pressure liquid-phase simulation load accumulation error test platform, which comprises three parts, namely a test bench, a constant force executingmechanism and a position feedback mechanism. The two mechanisms are fixed through the test bench. The constant force executing mechanism is used for pushing a simulation plunger to move in the axial direction through a high-precision ultrahigh-pressure liquid phase pump. The simulation plunger is matched with a force sensor. The force sensor is used for detecting the pressure borne by the simulation plunger. In order to ensure that the simulation load is kept constant, a fine adjustment mechanism is designed for adjustment and control. The position feedback mechanism obtains the measured numerical value of the stroke of the simulation plunger through a grating sensor, extracts an accumulated error and feeds back the accumulated error to a liquid phase pump control system.

Description

technical field [0001] The invention relates to a cumulative error testing platform, which belongs to the field of liquid chromatography analysis. Background technique [0002] As a simple, fast and effective analysis method, liquid chromatography is widely used in almost all fields of quantitative and qualitative analysis, including biochemistry, food analysis, pharmaceutical research, environmental analysis, inorganic analysis, etc. In the past ten years, the demand for chromatographic analysis has continued to develop in the direction of "higher precision", "higher pressure" and "faster analysis", which has also continuously promoted high-performance liquid chromatography instruments to have higher resolution, high analysis The development of ultra-high performance liquid chromatography with high efficiency and high sensitivity. [0003] High performance liquid chromatography (UHPLC) is generally composed of an infusion system (high-pressure pump, gradient device, reagen...

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Problems solved by technology

[0003] High performance liquid chromatography (UHPLC) is generally composed of an infusion system (high-pressure pump, gradient device, reagent bottle, etc.), a sampling system, a separation system, a detection system, etc., and its core key component - high-precision ultra-high pressure liquid pump technology Flow accuracy, accuracy, pressure pulsation and system delay volume are difficult to meet the requirements, which restricts the development of domestic UHPLC

To achieve high precision and high accuracy of flow rate requires high-precision ultra-high pressure liquid phase pump to have high-precision and low-pulsation micron motion precision shafting. Due to the comprehensive influence of the cumulative error of the screw pitch, the runout error of the bearing end face and the transmission error of the motor, the output accuracy of the shaft system of the high-precision ultra-high pressure liquid phase pump is still difficult to meet the requirements of UHPLC accuracy, and it is necessary to adopt high-precision ultra-high pressure liquid phase pump. Simulation load cumulative error test and compensation measures to eliminate principle error

[0004] Since the main error influencing factor affecting the output accuracy of the high-precision ultra-high pressure liquid phase pump is the cumulative error of the screw pitch, the traditional detection method of the cumulative error of the screw pitch only realizes the detection of the cumulative error of the screw pitch under no-load conditions

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