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Compound traditional Chinese medicine and application thereof in treatment of prostatic hyperplasia

A technology of prostatic hyperplasia and compound traditional Chinese medicine, which is applied in the field of traditional Chinese medicine, can solve the problems of obvious side effects and few varieties, and achieve the effect of treating prostatic hyperplasia

Active Publication Date: 2019-04-30
林嗣松 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] To sum up, in the current treatment methods for BPH, surgical treatment is prone to complications; there are not many varieties available for drug treatment, and the effective α1-ARs antagonists and 5-ARIs have obvious side effects, which have a negative effect on sexual function. There are different degrees of influence, and with the acceleration of the aging process, the number of BPH patients in all countries in the world is on the rise

Method used

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  • Compound traditional Chinese medicine and application thereof in treatment of prostatic hyperplasia
  • Compound traditional Chinese medicine and application thereof in treatment of prostatic hyperplasia
  • Compound traditional Chinese medicine and application thereof in treatment of prostatic hyperplasia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Chinese medicinal materials: 50g of Rauwolfia, 200g of Epimedium, 200g of Tongkat Ali, 200g of Cornus officinalis, 100g of cinnamon, and 100g of chives.

[0026] Pulverize and mix the above-mentioned Chinese medicinal materials to obtain the material; add it to the extraction kettle, and use supercritical CO 2 Extract, get compound Chinese medicine extract 12.56g (hereinafter referred to as product A); Wherein, extraction pressure is 26MPa, and extraction temperature is 55 ℃, CO 2 The flow rate is 50L / h, the extraction time is 90min, the temperature of the separation tank I is 45°C, and the pressure is 8MPa, and the temperature of the separation tank II is 40°C, and the pressure is 5MPa.

Embodiment 2

[0028] Chinese medicine decoction pieces: 200g of Rauwolfia, 500g of Epimedium, 500g of Tongkat Ali, 500g of Cornus officinalis, 500g of cinnamon, and 500g of chives.

[0029] Pulverize and mix the above-mentioned Chinese medicinal pieces to obtain the material; add it to the extraction kettle, and use supercritical CO 2 Extraction, get Chinese medicine extract 41.12g (hereinafter referred to as product B); Wherein, extraction pressure is 30MPa, and extraction temperature is 50 ℃, CO 2 The flow rate is 60L / h, the extraction time is 60min, the temperature of the separation tank I is 40°C, and the pressure is 10MPa, and the temperature of the separation tank II is 35°C, and the pressure is 6MPa.

Embodiment 3

[0031] Chinese medicinal materials: 50g of Rauwolfia, 100g of Epimedium, 100g of Tongkat Ali, 100g of Cornus officinalis, 100g of Cinnamon, 100g of Chives.

[0032] Pulverize and mix the above-mentioned Chinese medicinal materials to obtain the material; add it to the extraction kettle, and use supercritical CO 2 Extraction, get Chinese medicine extract 7.52g (hereinafter referred to as product C); Wherein, extraction pressure is 28MPa, and extraction temperature is 53-55 ℃, CO 2 The flow rate is 55L / h, the extraction time is 70min, the temperature of the separation tank I is 43-45°C, and the pressure is 9MPa, and the temperature of the separation tank II is 38-40°C, and the pressure is 6MPa.

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Abstract

The invention relates to a compound traditional Chinese medicine and an application thereof in treatment of prostatic hyperplasia. The compound traditional Chinese medicine comprises the following rawmaterials by weight: 0.5-2 parts of rauvolfia verticillate, 1-5 parts of herba epimedii, 1-5 parts of eurycoma longifolia, 1-5 parts of common macrocarpium fruit, 1-5 parts of cinnamon and 1-5 partsof semen allii tuberosi. The prescription of the compound traditional Chinese medicine originates from a proved prescription explained in words by ancestors of Sisong Lin, general manager of Xi'an praise sky biotechnology Co., Ltd. and verified to be safe and efficient through trial by non-governmental volunteers for more than 30 years. The compound traditional Chinese medicine is meticulous in pathogenesis, proper in compatibility, special in medicine and strong in power. The compound traditional Chinese medicine takes herba epimedii, common macrocarpium fruit and the like capable of tonifying liver and kidney as the main components, treats the weakness of kidney-yang as the basis, is supplemented by rauvolfia verticillate, aeurycoma longifolia extracts and the like capable of activatingqi to excrete water, dispersing blood stasis and treating stranguria, is matched with drugs of cinnamon and semen allii tuberosi extracts capable of tonifying kidney and supporting Yang, and treats disadvantage sign of blood stasis and bladder gasification; the whole prescription is used for syndrome differentiation and treatment, achieves whole regulation, can achieve the effect of both treatmentof symptoms and symptoms, and can effectively treat prostatic hyperplasia.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a compound traditional Chinese medicine and its application in treating benign prostatic hyperplasia. Background technique [0002] Benign prostatic hyperplasia (BPH), often called benign prostatic hyperplasia (BPH), is the most common disease causing voiding disorders in middle-aged and elderly men, and it is also one of the most common diseases in urology. With the aging of the global population, the incidence of benign prostatic hyperplasia increases with age, but when there are hyperplasia lesions, there may not be clinical symptoms. Most patients will have increased symptoms such as dysuria with age; the incidence rate in urban areas is higher than that in rural areas, and Ethnic differences also affect the degree of hyperplasia. The main manifestations are histological hyperplasia of prostatic stroma and glandular components, anatomical prostatic enl...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P13/08
CPCA61K36/185A61K36/24A61K36/296A61K36/40A61K36/54A61K36/8962A61K2236/37A61P13/08A61K2300/00
Inventor 林嗣松王四旺
Owner 林嗣松
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