An essence for promoting subcutaneous fat regeneration and its preparation process

A technology of subcutaneous fat and essence, applied in skin care preparations, cosmetic preparations, cosmetic preparations, etc., can solve the problems of safety risks, postoperative infection risks, postoperative facial asymmetry, etc., and achieve improved Anti-aging ability, easy to use, good effect

Active Publication Date: 2022-01-14
曾春晨
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problems of safety risk, postoperative infection risk and postoperative facial asymmetry in the existing medical cosmetology through surgical methods, the present invention provides an essence that promotes subcutaneous fat regeneration Liquid, its technical scheme is as follows: an essence for promoting subcutaneous fat regeneration, characterized in that, the formula is: SIS3 0.01~1.00%, SB431542 0.01~1.00%, sodium hyaluronate 0.05~1.5%, Pyrrolidone carboxylate 0.5%, olive oil 0.01~1%, glycerin 1~5%, Sepigel305 0.05~2.00%, the rest is deionized water, the sum of the above components is 100%;

Method used

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  • An essence for promoting subcutaneous fat regeneration and its preparation process
  • An essence for promoting subcutaneous fat regeneration and its preparation process
  • An essence for promoting subcutaneous fat regeneration and its preparation process

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0021] Specific Example 1: First, take 0.05% sodium hyaluronate, 0.5% pyrrolidone carboxylate, 0.05% Sepigel305, 1% glycerin, and 98.38% deionized water into the reaction tank, start stirring, and heat to 75 ~80°C, stir and disperse evenly; then, continue to stir and cool to below 37°C, then take 0.01% SIS3 and 0.01% SB431542 dissolved in 0.01% olive oil, add to the reaction tank and homogenize for 2-3 minutes, Stir to dissolve completely, end.

specific Embodiment 2

[0022] Specific embodiment 2: first take 1.5% sodium hyaluronate, 0.5% pyrrolidone carboxylate, 2.00% Sepigel305, 5% glycerin, and 88% deionized water and add them to the reaction tank, start stirring, and heat to 75 ~80°C, stir and disperse evenly; then, continue to stir and cool to below 37°C, then take 1% SIS3, 1% SB431542 dissolved in 1% olive oil, add to the reaction tank and homogenize for 2-3 minutes, Stir to dissolve completely, end.

specific Embodiment 3

[0023] Specific embodiment 3: first take 0.1% sodium hyaluronate, 0.5% pyrrolidone carboxylate, 2.00% Sepigel305, 5% glycerin, and 92.2% deionized water into the reaction tank, start stirring, and heat to 75 ~80°C, stir and disperse evenly; then, continue to stir and cool to below 37°C, then take 0.1% SIS3 and 0.1% SB431542 dissolved in 1% olive oil, add to the reaction tank and homogenize for 2-3 minutes, Stir to dissolve completely, end.

[0024] The present invention will be further described below in conjunction with the preparation of specific implementation components:

[0025] SIS3 and SB431542 are the core effective components for promoting subcutaneous fat regeneration in the present invention, respectively inhibiting signals at different nodes of the TGFbeta signaling pathway, and are configured according to different concentrations according to the experimental design. The specific experimental group formulations are as follows:

[0026]

[0027] The performance...

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Abstract

The invention relates to the field of skin anti-aging care products, in particular to an essence that promotes subcutaneous fat regeneration and its preparation process. The formula is: SIS3 0.01-1.00%, SB431542 0.01-1.00%, hyaluronic acid Sodium 0.05~1.5%, pyrrolidone carboxylate 0.5%, olive oil 0.01~1%, glycerin 1~5%, Sepigel305 0.05~2.00%, the rest is deionized water, the sum of the above components is 100%; the present invention Among them, SIS3 is a new type of specific Smad3 inhibitor, which can inhibit the phosphorylation of Smad3 and inhibit TGF-β and activin signaling. SB-431542 is a transforming growth factor β receptor (TGF-β Receptor) inhibitor, SIS3 and SB431542 are both Fat-soluble, and the molecular weight is all less than 800, easy to enter the basal layer and dermis of the skin through the stratum corneum of the skin, the invention is convenient to use, has a good effect, and can greatly improve the anti-aging ability of the skin.

Description

technical field [0001] The invention relates to the field of skin anti-aging care products, in particular to an essence for promoting subcutaneous fat regeneration and a preparation process thereof. Background technique [0002] With the continuous improvement of living standards, people pay more and more attention to health, especially skin care. Skin tissue is the largest tissue and organ of the human body, covering the surface of the human body and blocking the harmful effects of all harmful substances in nature on the living body. However, with the increase of age, the functions of skin tissues and organs are gradually aging. From an aesthetic point of view, it seriously affects people's enthusiasm for life; from a physiological point of view, it affects the effective protection of internal organs of the human body. Skin aging is a comprehensive Generally, as the age continues to grow, subcutaneous fat atrophy, collagen fibers and elastic fiber degeneration continue to ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/73A61K8/49A61K8/92A61K8/34A61Q19/00
Inventor 曾春晨杨俊涛史文飚赵凯范信梅
Owner 曾春晨
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