Application of traditional Chinese medicine composition in preparing medicines for improving immune function

A composition and technology of traditional Chinese medicine, applied in the application field of traditional Chinese medicine composition in the preparation of drugs for improving immune function, can solve the problems of insufficient Haima Bushen Pills, etc., and achieve the effects of improving humoral immune function, increasing content, and improving body immunity

Inactive Publication Date: 2019-05-31
津药达仁堂集团股份有限公司乐仁堂制药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although Haima Bushen Pills have been widely used for the above clinical symptoms, the indications of Haima Bushen Pills are not fully discovered at present.

Method used

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  • Application of traditional Chinese medicine composition in preparing medicines for improving immune function
  • Application of traditional Chinese medicine composition in preparing medicines for improving immune function
  • Application of traditional Chinese medicine composition in preparing medicines for improving immune function

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Embodiment 1 Chinese medicine composition and preparation method thereof

[0067] (a) Weigh 1875 parts of dog kidney, 40 parts of deer tendon, 7500 parts of fresh sparrow meat with the head removed, 930 parts of donkey kidney, 500 parts of dried sea rice, 750 parts of deer antler, 375 parts of hippocampus, 375 parts of sea maggot, 40 parts of leopard bone, 240 parts of gecko, 750 parts of ginseng, 625 parts of astragalus, 1000 parts of angelica, 5000 parts of rehmannia glutinosa, 5000 parts of aconite, 375 parts of cinnamon, 2500 parts of mother clove, 1250 parts of salted fennel, 750 parts of achyranthes 1250 parts of salt psoralen, 1875 parts of Codonopsis pilosula, 750 parts of poria cocos, 1500 parts of yam, 750 parts of Eucommia charcoal, 375 parts of dog ridge, 5000 parts of cistanche deserticola from wine, 1250 parts of walnut kernel, 2000 parts of epimedium, 1250 parts of sautéed shayuanzi with salt, 2000 parts of raspberry, 750 parts of medlar, 750 parts of win...

Embodiment 2

[0072] The impact of embodiment 2 Chinese medicine composition on non-specific immunity

[0073] The immunosuppressive model of mice induced by injection of cyclophosphamide hydrochloride was adopted. Select 84 healthy Kunming mice, half male and half female, body weight (18-20) g, randomly grouped, 12 mice in each group, normal control group, model control group, lentinan 100mg / kg, Guilingji 0.24 g / kg, traditional Chinese medicine composition (0.55, 1.1, 2.2) g / kg three dose groups, a total of 7 groups. Each dose group was administered intragastrically once a day for 14 consecutive days, with an administration volume of 20ml / kg.bw, the normal control group was given the same amount of distilled water, and the model group was given a corresponding volume of 0.5% CMC-Na. On the 11th day of the experiment, except for the normal control group, all other animals were intraperitoneally injected with cyclophosphamide hydrochloride 80 mg / kg every day for 3 consecutive days. On the ...

Embodiment 3

[0086] The influence of embodiment 3 Chinese medicine composition on humoral immunity

[0087] The immunosuppressive model of mice induced by injection of cyclophosphamide hydrochloride was adopted. Select 70 healthy Kunming mice, body weight (18-20) g, and divide them into random groups, 10 mice in each group. In the experiment, normal control group, model control group, Lentinus polysaccharide 100mg / kg, Guilingji 0.24g / kg, Three dose groups of Chinese medicine composition (0.55, 1.1, 2.2) g / kg, 7 groups in total. Each administration group was intragastrically administered once a day, the normal control group was given the same amount of distilled water, and the model control group was given the corresponding volume of 0.5% CMC-Na, for 14 consecutive days, the administration volume was 20ml / kg.bw. On the 9th day of the experiment, except for the normal control group, which was intraperitoneally injected with a corresponding amount of normal saline, all other animals were int...

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Abstract

The invention relates to the field of traditional Chinese medicine, in particular to application of a traditional Chinese medicine composition in preparing medicines for improving an immune function.The traditional Chinese medicine composition comprises dog kidney, deer's sinew, fresh sparrow meat with the head, the mouth and the claws removed, donkey kidney, dried shrimp, cornu cervi pantotrichum, sea horse, cherula, prepared leopard bone and gecko. Not only does the traditional Chinese medicine composition have effects of nourishing yin and the kidney and strengthening the brain, but also through tests it is found that the traditional Chinese medicine composition can effectively improve non-specific immune functions and humoral immune functions, that is, enhance immune functions of thebody. The traditional Chinese medicine composition is prepared from natural materials, and the therapeutic effect is achieved by utilizing the active ingredients of the traditional Chinese medicines and the compatibility relationship between the various medicinal materials. Based on the existing indications, a new indication of the traditional Chinese medicine composition is found, and as a medicine for improving immunity of the body, the traditional Chinese medicine composition provides a new direction for the full utilization and development of the medicines.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to the application of a traditional Chinese medicine composition in the preparation of medicines for improving immune function. Background technique [0002] Haima Bushen Pill is a famous clinical prescription, which is extracted from 36 medicinal materials such as deer antler, deer kidney and hippocampus. Shortness of breath, backache and leg pain, forgetfulness, shortness of breath and other clinical symptoms. Although Haima Bushen Pills have been widely used for the above clinical symptoms, the indications of Haima Bushen Pills have not been fully discovered so far. [0003] In view of this, the present invention is proposed. Contents of the invention [0004] The object of the present invention is to provide a kind of application of Chinese medicine composition in the preparation of the medicine that improves non-specific immunity and / or humoral immunity, provide...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/48A61K35/32A61K35/57A61K35/612A61K35/60A61K35/62A61K35/583A61K36/804A61K36/8945A61P37/04A61K35/02
Inventor 金兆祥王琳庞纪平张宇王玉晶范迪郭琳
Owner 津药达仁堂集团股份有限公司乐仁堂制药厂
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