A traditional Chinese medicine suppository for treating acute cerebral infarction and its preparation method

A technology for cerebral infarction and acute phase, which is applied in the direction of pharmaceutical formula, suppository delivery, medical preparations containing active ingredients, etc., to achieve the effect of high safety factor

Active Publication Date: 2020-10-02
JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Honey Jiandao is the earliest traditional Chinese medicine suppository, derived from Zhang Zhongjing's "Treatise on Febrile and Miscellaneous Diseases". It is made of pure honey (pharmaceutical grade). It is safe, effective and has no side effects. It is still widely used in the treatment of chronic constipation. There are few research data on the application of infarction

Method used

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  • A traditional Chinese medicine suppository for treating acute cerebral infarction and its preparation method

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Experimental program
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Effect test

Embodiment 1

[0019] The raw materials of the present invention are weighed according to the following parts by weight: honey (food grade), pig bile powder, mass ratio: 3:1.

[0020] Weigh honey and pig bile powder according to the above ratio, pure honey (pharmaceutical grade) is boiled and refined in a copper furnace with slow fire, after reaching a certain consistency, blend the dry powder of pig bile, mix well, continue to boil for 20 minutes, cool to room temperature, Put in clean glass or ceramic utensils, seal and store at room temperature for later use.

[0021] The traditional Chinese medicine suppository of the present invention is used to treat visceral obstruction or constipation in the acute stage of cerebral infarction.

Embodiment 2

[0023] The clinical authenticity research has been preliminarily carried out by using the present invention, and more than 500 patients with acute cerebral infarction have been clinically applied. The clinical test results obtained are briefly summarized as follows:

[0024] 1. Case selection: A total of 1271 patients with acute cerebral infarction were hospitalized in the Department of Neurology, Jiangsu Provincial Hospital of Integrated Traditional Chinese and Western Medicine, including 597 patients in the traditional Chinese medicine suppository treatment group, 308 males and 289 females, the oldest being 92 years old and the youngest being 31 years old , the average age was 68.13±5.2 years old; the blank control group was 674 cases, 348 males and 326 females, the oldest was 82 years old, the youngest was 29 years old, and the average age was 65.28±5.3 years old. There were no significant differences in age, gender and disease between the two groups (P>0.05), which were com...

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Abstract

The invention discloses a traditional Chinese medicine suppository for treating acute cerebral infarct and a preparation method of the traditional Chinese medicine suppository. According to the traditional Chinese medicine suppository for treating the acute cerebral infarct and the preparation method of the traditional Chinese medicine suppository, the suppository is prepared for rectal administration and bowel relaxing by combining honey and pig's bile in a certain proportion, thereby being capable of more effectively purging the viscera to eliminate heat, descending the turbid, ascending thelucidity, removing pathogenic heat from the blood and toxic material from the body for resuscitation, and reducing the inflammatory reaction of the acute cerebral infarct to achieve the purpose of reducing cerebral edema, protecting the brain and improving long-term prognosis. The traditional Chinese medicine suppository has the advantages that the curative effect is definite, the suppository issimple, convenient and practicable, has no toxic and side effects, the effective rate reaches 86.55%, and the suppository has the good curative effect and potential clinical application value.

Description

technical field [0001] The invention relates to a traditional Chinese medicine external therapy suppository for treating acute cerebral infarction and improving prognosis, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Cerebral infarction is a common clinical disease with high morbidity, high mortality, high disability rate and high recurrence rate. Intracellular inflammatory response and cerebral edema caused by cerebral ischemia and hypoxia are the main pathological manifestations of acute cerebral infarction. Reports at home and abroad believe that the dynamic changes of oxidative stress and immune-inflammatory mechanisms in serum and brain are closely related to the severity of stroke patients and whether the disease is likely to change. Western medicines commonly used in clinic with anti-platelet aggregation and anti-arteriosclerosis, as well as Chinese patent medicines with the functions of promoting blood circulation...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/644A61K9/02A61P9/10A61P1/10A61K35/413
Inventor 刘红权王省成小兰李静波房铭铭高梅龚杰
Owner JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
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