Simulation experiment and non-invasive blood glucose detection method based on body heat production-dissipation model

A simulation experiment and blood sugar detection technology, which is applied in the field of blood sugar detection, can solve the problems of blood sugar calculation errors, physiological cycle affecting human body temperature, etc., and achieve the effects of low cost, elimination of body temperature fluctuations, and simple operation

Active Publication Date: 2020-02-18
江苏精策医疗科技有限公司
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Problems solved by technology

[0006] The purpose of the present invention is to provide a simulation experiment and non-invasive blood sugar detection method based on the body heat production-heat dissipation model to solve environmental factors, physiological cycles, fluctuations in physical conditions, use of hypoglycemic drugs and insulin, exercise and drinking tea Bathing and other living habits affect the body temperature, which makes the technical problem of blood sugar calculation error

Method used

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  • Simulation experiment and non-invasive blood glucose detection method based on body heat production-dissipation model
  • Simulation experiment and non-invasive blood glucose detection method based on body heat production-dissipation model
  • Simulation experiment and non-invasive blood glucose detection method based on body heat production-dissipation model

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Embodiment 1

[0206] The structure of the body heat production-radiation model of the present embodiment is as follows: figure 1 shown. The body heat generation-radiation model includes a hollow cylinder (1) with a sealed bottom and an open top, and the hollow cylinder (1) simulates a human body heat capacity. The height of the inner wall of the hollow cylinder (1) is lower than the height of the outer wall, and a polymer film (2) is pasted on the outer wall of the hollow cylinder (1). The model also includes a loam cake (3), simulated body fluid (4), Temperature probe (5), fixing plate (6) and temperature sensor wire (7). The upper cover (3) is arranged on the opening of the hollow cylinder (1), and the upper cover (3) is provided with an upper cover through hole (8) along the central axis. The simulated body fluid (4) is arranged in the cavity of the hollow cylinder (1). The fixed plate (6) is sleeved on the top of the temperature probe (5), and the diameter of the fixed plate (6) is s...

Embodiment 2

[0232] According to the above simulation experiment results, the relationship between the temperature change of the simulated heat storage body and the glucose concentration can be characterized by the characteristic parameters of the temperature dynamic change. Table 2 is a set of measured data. The simulated body temperature for preheating of the heat capacitor is 36.2°C. The probe preheat temperature is 35.2°C. The environmental conditions are: 22.5°C, 50%, 0m / s. Five glucose concentrations were selected. The temperature change of the simulated body fluid is measured and recorded after the thermal mass body is placed in the environmental simulation box, and is recorded once every minute, and the test is completed after 30 minutes.

[0233] Table 2. Relationship between heat mass temperature and glucose concentration

[0234]

[0235]

[0236] Based on Table 2, the time-domain diagram of the temperature of the body fluid with five glucose concentrations changing wi...

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Abstract

The invention discloses a body heat production-heat dissipation model, a simulation experiment and a non-invasive blood glucose detecting method thereof. The body heat production-heat dissipation model comprises a hollow cylinder with a sealed bottom part and an opened top part; the inner wall height of the hollow cylinder is lower than the outer wall height; and a polymer film is attached to theouter wall of the hollow cylinder. The body heat production-heat dissipation model also comprises an upper cover, a simulated body fluid, a temperature probe, and a temperature sensor wire, wherein the upper cover covers the opening of the hollow cylinder; the upper cover is provided with an upper cover through hole along a central axis; the simulated body fluid is placed in the cavity of the hollow cylinder; the temperature probe passes through the upper cover through hole and is inserted into the simulated body fluid; and one end of the temperature sensor wire is connected to the top end ofthe temperature probe. The model is used to design the simulation experiment for non-invasive blood glucose detection, the interference factors of the traditional metabolic heat methods such as body temperature fluctuations, physical conditions, physiological cycles, environmental conditions and drug effects can be effectively reduced or eliminated, and the blood glucose detection accuracy is improved.

Description

technical field [0001] The invention relates to the technical field of blood sugar detection, in particular to a simulation experiment based on a body heat generation-radiation model and a non-invasive blood sugar detection method. Background technique [0002] Calculating the current blood glucose level by measuring the body's metabolic heat has become one of the mainstream methods for non-invasive blood glucose detection. Based on the theory of energy conservation, it uses temperature sensors, humidity sensors, radiation sensors and blood oxygen sensors to collect temperature and physiological signals on the skin surface (mainly the finger surface), and then combines with a digital signal processor to produce a non-invasive blood glucose detection device. . People use MEMS technology to integrate a variety of sensors to improve their reliability as much as possible, especially to improve the sensitivity and signal-to-noise ratio of the sensor, optimize the mathematical mo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/145
Inventor 何宗彦王艺融
Owner 江苏精策医疗科技有限公司
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