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Traditional Chinese medicine composition for repairing endometrium and assisting reproduction

A technology of endometrium and composition, which is applied in the direction of drug combination, drug delivery, and medical formula, can solve the problems of repeated implantation failure of high-quality embryos, low number of patients, and non-targeted drugs, and achieve low side effects, convenient sources, and effective treatment. low cost effect

Inactive Publication Date: 2019-07-02
湖北省妇幼保健院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Furthermore, modern assisted reproductive technology, especially in vitro fertilization-embryo implantation (Invitro fertility-embryoimplantation, IVF-ET) is the most direct method to treat infertility, but the key to successful implantation and pregnancy depends on the relationship between the embryo and the endometrium. The current clinical problems for this technology are: relatively low positive pregnancy rate (30% to 60%) and repeated implantation failure (RIF) of high-quality embryos in some patients, and this high cancellation rate and The main factor of RIF lies in the endometrium
[0004] At present, hormone regulation, application of anticoagulants to increase microcirculation, stimulation of endometrium formation by light scraping, and intrauterine injection of granulocyte colony-stimulating factor are mainly used for clinical treatment of endometrium. There is no targeted drug on the market.

Method used

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  • Traditional Chinese medicine composition for repairing endometrium and assisting reproduction
  • Traditional Chinese medicine composition for repairing endometrium and assisting reproduction

Examples

Experimental program
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Effect test

Embodiment 1

[0036] A traditional Chinese medicine composition for repairing endometrium and assisting pregnancy, which is composed of external medicine and internal medicine. 10 parts of medicine, 10 parts of cinnamon, 10 parts of peach kernel, 6 parts of male clove, 10 parts of white mustard seed, 8 parts of agarwood, 10 parts of Morinda officinalis; the internal medicine is made of the following components by weight: rehmannia glutinosa 8 10 parts of Salvia miltiorrhiza, 8 parts of dodder seed, 8 parts of fairy spleen, 8 parts of Morinda officinalis, 8 parts of roasted tortoise shell, 8 parts of Poria cocos, 4 parts of fried red peony root, 8 parts of angelica, and 10 parts of Mildew Spatholobus.

[0037] A traditional Chinese medicine preparation for repairing endometrium and assisting pregnancy prepared by using the traditional Chinese medicine composition, comprising two parts: powder for navel made by external medicine and water decoction made by internal medicine.

[0038]The prepa...

Embodiment 2

[0043] A traditional Chinese medicine composition for repairing endometrium and assisting pregnancy, which consists of external medicine and internal medicine. The external medicine is made of the following components by weight: 15 parts of Shufu tablets, 15 parts of frankincense 15 parts of medicine, 15 parts of cinnamon, 15 parts of peach kernel, 6 parts of male clove, 15 parts of white mustard seed, 12 parts of agarwood, 15 parts of Morinda officinalis; the internal medicine is made of the following components by weight: Shudi 13 15 parts of Salvia miltiorrhiza, 13 parts of dodder seed, 13 parts of fairy spleen, 13 parts of Morinda officinalis, 13 parts of roasted tortoise shell, 13 parts of Poria cocos, 10 parts of fried red peony root, 13 parts of angelica, and 15 parts of Mildew Spatholobus.

[0044] A traditional Chinese medicine preparation for repairing endometrium and assisting pregnancy prepared by using the traditional Chinese medicine composition, comprising two pa...

Embodiment 3

[0050] A traditional Chinese medicine composition for repairing endometrium and assisting pregnancy, which is composed of external medicine and internal medicine. 12 parts of medicine, 12 parts of cinnamon, 12 parts of peach kernel, 6 parts of male clove, 12 parts of white mustard seed, 10 parts of agarwood, 12 parts of Morinda officinalis; the internal medicine is made of the following components by weight: rehmannia 10 12 parts of Salvia miltiorrhiza, 10 parts of dodder seed, 10 parts of fairy spleen, 10 parts of Morinda officinalis, 10 parts of broiled tortoise shell, 10 parts of Poria cocos, 6 parts of fried red peony root, 10 parts of angelica, and 12 parts of Mildew Spatholobus.

[0051] A traditional Chinese medicine preparation for repairing endometrium and assisting pregnancy prepared by using the traditional Chinese medicine composition, comprising two parts: powder for navel made by external medicine and water decoction made by internal medicine.

[0052] The prepar...

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Abstract

The invention provides a traditional Chinese medicine composition for repairing endometrium and assisting reproduction. The traditional Chinese medicine composition comprises two parts, an external medicine and an internal medicine, wherein the external medicine is composed of processed monkshood, processed frankincense, myrrh, cinnamon, peach kernel, flos caryophylli, sinapis alba, aquilaria wood, and morinda officinalis with a specific proportion, the internal medicine is composed of Radix Rehmanniae Preparata, red sage root, Semen Cuscutae, aerial parts of epimedium, morinda officinalis, roasted tortoiseshell, Poria cocos, fried radix paeoniae rubra, Chinese angelica, and spatholobus stem. The traditional Chinese medicine composition has the advantages of convenient source of raw material, simple processing method, and wide application prospect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for repairing endometrium and assisting pregnancy. Background technique [0002] Endometrial injury caused by intrauterine operation curettage, abortion, etc. and poor endometrial receptivity caused by low levels of sex hormones in ovarian hypofunction are one of the common causes of infertility in women of childbearing age in my country. [0003] Furthermore, modern assisted reproductive technology, especially in vitro fertilization-embryo implantation (Invitro fertility-embryoimplantation, IVF-ET) is the most direct method to treat infertility, but the key to successful implantation and pregnancy depends on the relationship between the embryo and the endometrium. The current clinical problems for this technology are: relatively low positive pregnancy rate (30% to 60%) and repeated implantation failure (RIF) of high...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/835A61K36/804A61K9/14A61K9/00A61K47/38A61P15/08A61K35/586
CPCA61K9/0014A61K9/0095A61K9/146A61K35/586A61K36/076A61K36/232A61K36/296A61K36/31A61K36/324A61K36/328A61K36/39A61K36/43A61K36/486A61K36/537A61K36/54A61K36/61A61K36/65A61K36/71A61K36/714A61K36/736A61K36/746A61K36/804A61K36/835A61K2236/331A61K2236/39A61P15/08A61K2300/00
Inventor 黄晓桃张晓燕梁少荣葛曼王璐
Owner 湖北省妇幼保健院
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