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Efficient generation method of porous scaffold with complex morphology

A porous support and topography technology, which is applied in special data processing applications, instruments, electrical digital data processing, etc., can solve problems such as low efficiency, and achieve the effects of improving efficiency, reducing time complexity, and making the method stable and reliable.

Active Publication Date: 2019-07-05
ZHEJIANG UNIV
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Problems solved by technology

[0007] In order to solve the shortcomings of the low efficiency of existing methods for generating porous scaffolds in three-dimensional space, the present invention provides an efficient method for generating porous scaffolds with complex shapes

Method used

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  • Efficient generation method of porous scaffold with complex morphology
  • Efficient generation method of porous scaffold with complex morphology
  • Efficient generation method of porous scaffold with complex morphology

Examples

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Embodiment

[0046] Typical implementation examples of the present invention are as follows:

[0047] Input the G surface function expression f(x,y,z)=sin(τx)cos(τy)+sin(τz)cos(τx)+sin(τy)cos(τz)=0, the shape of the nose surface is determined by T Spline surface modeling, porous support wall thickness w=1mm, slice discrete thickness d=0.1mm, select one of the topographic slice layers, and calculate different numbers by setting different layered discrete grid resolution r or surface parameters Comparing the computational efficiency of different strategies. Such as Figure 7 As shown, when the period of the G curved surface is relatively large, the method of the present invention first obtains the triangular interpolation grid within the contour range of the topography slice layer and then interpolates, that is, the method of first interpolating and then interpolating, which is different from the traditional method that first interpolates and then interpolates There is little difference in...

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Abstract

The invention discloses an efficient generation method of a porous scaffold with complex morphology. The efficient generation method comprises the following steps: inputting a three-cycle minimal curved surface expression, layering discrete grid resolution, modeling a T-spline curved surface with complex morphology of the porous scaffold, slicing discrete thickness, and dispersing the T-spline curved surface into a morphology slice layer; generating an upper triangular interpolation grid and a lower triangular interpolation grid in the envelope region range of the morphology slice layer according to the envelope region range of the morphology slice layer and the layered discrete grid resolution; according to the triangular interpolation grid in the contour range of the topographic slice layer, calculating a corresponding three-period minimal curved surface layered slice contour through linear interpolation; offsetting the contour of the three-period minimal curved surface layered sliceto generate a closed layered filling region, and carrying out Boolean operation on the closed layered filling region and a topographic slice layer region; and finally outputting the layered filling area of the porous scaffold with the complex morphology. The method is stable and reliable, and the layered filling area can be efficiently generated in the two-dimensional space and directly used foradditive manufacturing.

Description

technical field [0001] The invention relates to the technical fields of computer aided design (CAD) and tissue engineering, in particular to a method for efficiently generating porous scaffolds with complex shapes. Background technique [0002] With the continuous development of tissue engineering and regenerative medicine technology, more and more biological tissues can be reproduced and cultured outside the body. Due to some external traumas, some defective human organs such as noses and ears need to be artificially transplanted to meet the functional and aesthetic requirements. Porous scaffolds are one of the research focuses in the field of tissue engineering, providing a basic place for cell proliferation and differentiation. Generally speaking, tissue engineering has two main requirements for porous scaffolds: First, in terms of shape, in order to fit the transplanted tissue, it is generally required that the porous scaffold also have a complex shape consistent with t...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F17/50
CPCG06F30/20
Inventor 冯嘉炜傅建中林志伟商策
Owner ZHEJIANG UNIV
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