Traditional Chinese medicine composition and application thereof, medicine containing composition for epilepsy treatment and preparation method

Abstract

The invention provides a traditional Chinese medicine composition and application thereof, a medicine containing the composition for epilepsy treatment and a preparation method. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 5-15 parts of moth cocoon, 8-10 parts of calculus bovis, 50-70 parts of tabasheer, 85-95 parts of radix curcumae, 10-20 parts of cinnabaris and 40-50 parts of alumen. The traditional Chinese medicine composition provided by the invention can be applied to preparing the epilepsy treatment medicine. The prepared epilepsy treatment medicine provided by the invention can effectively reduce epileptic seizure of a pilocarpine rat and improve cognition, and the toxic and side effects of the medicine are small, so that the damage to neurons can be effectively reduced.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a traditional Chinese medicine composition and application thereof, a medicine for treating epilepsy comprising the same and a preparation method thereof. Background technique [0002] Epilepsy is a common chronic disease of the nervous system, with an annual incidence of about 23 / 100,000 in my country. According to different clinical manifestations, epilepsy can be divided into five types: generalized tonic-clonic seizures, simple partial seizures, complex partial seizures, absence seizures, and status epilepticus. It belongs to the central nervous system disease and is a chronic disease that can persist for several years or even decades, so it can cause serious adverse effects on the patient's body and mind, and bring great harm to the patient and his family. pain of. Therefore, there is an urgent need for the medical community to develop a drug for the treatment of epilepsy, ...

AI Technical Summary

Problems solved by technology

About two-thirds of patients with epilepsy can control their condition with the above anti-epileptic drugs, but there are still one-third of epilepsy patients who are ineffective with existing drugs

And most of these drugs are artificially synthesized chemical drugs, which have unavoidable toxic and side effects.

[0004] CN109700853A discloses a composition and its application in the preparation of a pharmaceutical composition for preventing and treating epilepsy, which provides a pharmaceutical composition containing cannabidiol, tetrahydrocannabinol, cannabinol, and hemp seed oil, although it can prevent epilepsy Epilepsy, but due to the use of more components such as cannabidiol or tetrahydrocannabinol, the side effects are greater

The experimental results of this patent show that when used within a safe dose range, it can significantly prolong the latency period of convulsions in mice, reduce the mortality rate, and restore the damage and death of hippocampal neurons after epileptic injury in mice, and there is a certain dose-related drug effect , but its application range is narrow

Images