Marker combination for predicting death due to severe ionizing radiation injury

Abstract

The invention discloses a marker combination for predicting death due to severe ionizing radiation injury. The invention provides a marker combination which can be taken as an index for predicting thesurvival and death of mice under severe radiation, and provides application of the marker combination to the prediction of the death rate in severe radiation. The marker combination is of important significance in the classified treatment of on-site injured people, particularly a large scale of irradiated people in nuclear explosion, nuclear accidents and nuclear terrorist attack.

Description

technical field [0001] The invention relates to the field of early detection and rapid treatment of nuclear radiation damage and acute radiation sickness, in particular to a marker combination for predicting death from severe ionizing radiation damage. Background technique [0002] Severe ionizing radiation can cause death of humans or animals, but if active response and symptomatic treatment are given early after exposure, some of the severely exposed people can survive. In large-scale nuclear radiation such as nuclear weapon explosions and nuclear power plant accident sites, large-scale populations, including rescuers, may receive large doses of exposure and cause severe ionizing radiation damage. Therefore, a fast and reliable diagnostic classification method is needed to distinguish The exposure dose of the exposed population can be used to infer the degree of radiation damage. For those severely exposed, treatment should be given as soon as possible. The earlier this pa...

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Problems solved by technology

[0004] To date, no studies have used plasma protein and cytokine expression levels to predict mortality or likelihood of death in irradiated animals

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