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Tumor microsphere profile detection method and device based on u-net network model

A network model and contour detection technology, which is applied in image analysis, image enhancement, instruments, etc., can solve the problems of low accuracy rate of the edge contour of tumor microspheres and low accuracy rate of tumor microsphere size, achieving high accuracy and improving Accuracy, the effect of improving the ability to extract features

Active Publication Date: 2020-11-20
INST OF MEDICAL DEVICES (SUZHOU) SOUTHEAST UNIV
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Problems solved by technology

[0005] The present invention provides a method and device for detecting the contour of tumor microspheres based on the U-net network model to solve the problem that the accuracy of the edge contour of tumor microspheres obtained by using the prior art is low, which leads to The accuracy of tumor microsphere size is also low

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  • Tumor microsphere profile detection method and device based on u-net network model
  • Tumor microsphere profile detection method and device based on u-net network model
  • Tumor microsphere profile detection method and device based on u-net network model

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Embodiment Construction

[0023] BACKGROUND binding known, prior art, according to laboratory personnel typically incubation time, the captured image microspheres tumor, then the tumor outline the contour of the edge of the image of the microspheres obtained, measurement tool used to obtain the final diameter of the edge profile, microspheres obtained and the tumor diameter calculated based on the area. Because in this process, the edge profile of the tumor obtained from the microspheres are manually outlined, the accuracy is lower, also resulting in a lower accuracy in accordance with the size of the tumor microspheres calculated edge profile. To solve this problem, embodiments of the present invention provides a microsphere tumor contour detection method and apparatus based on the U-net network model.

[0024] Below with the accompanying drawings, detailed description of the embodiment of the present invention provides microspheres tumor contour detection method and apparatus U-net network model.

[0025...

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Abstract

The invention discloses a tumor microsphere contour detection method and device based on a U-net network model, and the method comprises the steps of training a built to-be-trained U-net network modelthrough a training image, and generating a trained U-net network model; in the to-be-trained U-net network model, except the last convolution block, connecting a residual structure behind each rest convolution block to sum the input image of the convolution block and the output image of the convolution block as the input image of the next convolution block; and generating an edge contour curve ofthe tumor microsphere image to be detected by using the trained U-net network model. The edge contour curve of the to-be-detected tumor microsphere image obtained in the method is obtained by using the trained U-net network model, the accuracy is higher, and the size of the tumor microsphere is calculated by using the edge contour curve subsequently, so that a calculation result with higher accuracy can be obtained.

Description

Technical field [0001] The present invention relates to a contour detection technology, and particularly relates to a tumor microsphere contour detection method and apparatus U-net network model. Background technique [0002] In the three-dimensional cell culture of tumor cells, it is necessary according to the growth and invasiveness of tumor cell detection, cytotoxicity study on the compound of the tumor cells. Based on this, the three-dimensional cell culture of tumor cells during tumor morphology requires the contour of the microspheres according to culture time culture, and measure the size of the recording, wherein the microspheres refers to the tumor sphere composed of a plurality of tumor cells, may be employed tumor area microspheres microspheres measure tumor size. [0003] The diameter of the prior art, according to the experimental incubation time will usually, the captured image microspheres tumor, then the tumor outline the contour of the edge of the image of the mi...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/00
CPCG06T7/0012G06T2207/20081G06T2207/20084G06T2207/30096
Inventor 顾忠泽陈早早马宁陈阳孙仕琪徐俊叶欢张静葛健军
Owner INST OF MEDICAL DEVICES (SUZHOU) SOUTHEAST UNIV