Lactobacillus jensenii and application thereof for preparing vaginal bacteriostatic drugs

A technology of Lactobacillus jannis and drugs, applied in the field of microorganisms, can solve the problems of not having the ability to inhibit vaginal pathogenic bacteria, and achieve the effect of superior vaginal epithelial cell adhesion, active and stable biological characteristics, and inhibition of Candida albicans
CN110540945AActive Publication Date: 2019-12-06广东强基药业有限公司 +2

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
广东强基药业有限公司
Publication Date
2019-12-06

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Abstract

The invention provides lactobacillus jensenii and application thereof for preparing vaginal bacteriostatic drugs. The lactobacillus jensenii is deposited in the China General Microorganisms CollectionCenter of China Committee for Culture Collection of Microorganisms, and the preservation number is CGMCC No. 14112. Research on the metabolic performance of the lactobacillus jensenii provided by theinvention discovers that, compared to ordinary lactobacillus jensenii, the strain has high lactic acid production capacity, high hydrogen peroxide production capacity, high bacteriostatic ability topathogenic bacteria, and outstanding vaginal epithelial cell adhesion ability. Based on the new properties discovered above, the invention determines a new use of the lactobacillus jensenii for preparing the vaginal bacteriostatic drugs, and the vaginal bacteriostatic drugs can realize treatment of a variety of bacterial vaginal diseases. The bactericidal agent provided by the invention has obvious effects on bacterial vaginal diseases, is safe and non-toxic, has good stability, and can be stored for a long time. The invention also relates to the use of the lactobacillus jensenii in drugs forprevention and / or treatment of gynecological diseases.
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Description

technical field

[0001] The invention relates to the technical field of microorganisms, and further relates to the regulation of vaginal micro-ecological environment and the treatment of bacterial vaginal diseases, in particular to a kind of Lactobacillus jannis and its application for preparing vaginal bacteriostatic drugs. Background technique

[0002] There are a variety of microorganisms in the vagina of healthy women, and they form a vaginal micro-ecological system that restricts, coordinates and dynamically balances with the host and the environment. The vaginal flora of healthy women is mainly composed of Lactobacillus, including Lactobacillus plantarum, Lactobacillus jansii, Lactobacillus gasseri, Lactobacillus crispatus, Lactobacillus vaginal, Lactobacillus jansii, etc. Under normal circumstances, Lactobacillus can protect the vagina. When the Lactobacillus in the vaginal microecology is disturbed, it can lead to the invasion of pathogenic bacteria and cause vaginiti...

Claims

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