Packaging for dry tissue prosthetic heart valve

A heart valve and prosthesis technology, which is used in the packaging field of "dry" tissue prosthetic heart valves, can solve the problems of valve prosthesis tissue drying, insufficiency, and valve not closing properly.

Active Publication Date: 2019-12-20
MEDTRONIC VASCULAR INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Possible problems with the valve include: stenosis, where the valve does not open properly; and/or incompetence or regurgitation, where the valve does not close properly
In other valve prosthesis packaging,

Method used

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  • Packaging for dry tissue prosthetic heart valve
  • Packaging for dry tissue prosthetic heart valve
  • Packaging for dry tissue prosthetic heart valve

Examples

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Embodiment Construction

[0033] Specific embodiments of the present application are now described with reference to the drawings, wherein like reference numerals indicate identical or functionally similar elements. The terms "distal" and "proximal" are used in the description below with respect to position or orientation relative to the treating clinician. "Distal" or "distally" is a location or in a direction away from the clinician. "Proximal" and "proximally" are a position near or in a direction towards the clinician. As used herein with reference to an implanted prosthetic heart valve, the terms "distal" and "outflow" are understood to mean downstream in the direction of blood flow, while the terms "proximal" or "inflow" are understood to mean blood flow. upstream in the flow direction.

[0034] As mentioned herein, stented transcatheter prosthetic heart valves that can be used in and / or as part of various systems, devices, and methods can assume a variety of different configurations, such as h...

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PUM

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Abstract

The present invention provides 'dry' packaging in which a prosthetic heart valve is packaged within a container with hydrogel (116) that can be provided in many forms. Certain embodiments include hydrogel (116) that is preloaded with glycerol or the like. The hydrogel regulates the humidity within the container through a diffusion-driven mechanism if a gradient of humidity between the inside and the outside of the hydrogel exists. Humidity regulation is important to prevent the tissue of the valve structure from drying out. When the partially-hydrated hydrogel (116) is present within container, which is saturated with air of a predefined humidity, the water molecules from the air will be absorbed by the hydrogel if the air humidity is high (i.e. when the thermodynamics favor hydrogel hydration) or vice versa. Various embodiments are configured to also house at least a portion of a delivery device for delivering the prosthetic heart valve.

Description

[0001] Cross References to Related Applications [0002] This non-provisional patent application claims the benefit of the filing date of U.S. Provisional Patent Application Serial No. 62 / 500,046, filed May 2, 2017, the entire teachings of which are incorporated herein by reference. Background technique [0003] The disclosed embodiments relate to packaging for a "dry" tissue prosthetic heart valve with or without a portion of a delivery device. Also disclosed are methods of packaging a transcatheter heart valve with or without a portion of a delivery device. [0004] The human heart consists of four heart valves that determine the path of blood flow through the heart: the mitral, tricuspid, aortic, and pulmonary valves. The mitral and tricuspid valves are atrioventricular valves located between the atria and ventricles, while the aortic and pulmonary valves are semilunar valves located in the arteries leaving the heart. Ideally, the native leaflets of a heart valve move awa...

Claims

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Application Information

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IPC IPC(8): B65D81/18A61F2/00B65D81/22A61F2/24
CPCA61F2/2412A61L2/206B65D81/18A61L2/08A61L2/208A61L2/26A61L2202/182A61L2202/21B65D81/22A61F2/0095A61F2/2418
Inventor R·瑞安D·克拉克K·加德Y·郭B·黄Y·达雷卡L·莱曼W·王L·麦克金利P·德威鲁克斯J·杜德尼T·蒂恩K·欧尔尼
Owner MEDTRONIC VASCULAR INC
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