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How to make Grape Seed Extract Tablets

A production method and technology of grape seeds, which are applied in the direction of medical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of few beneficial ingredients, bad teeth and difficulty in eating, and achieve rapid improvement. Effect of drying, reducing redeposition and improving quality

Active Publication Date: 2021-11-05
BRAVEIY BIOTECHNOLOGY (ANHUI) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, grape seeds are usually eaten directly for digestion and absorption. Because grape seeds are bitter and hard, it is difficult for the elderly and children or those with bad teeth to eat, and the beneficial ingredients of grape seeds are rarely absorbed. Therefore, Grape seeds need to be processed for easy consumption and absorption

Method used

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  • How to make Grape Seed Extract Tablets
  • How to make Grape Seed Extract Tablets
  • How to make Grape Seed Extract Tablets

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] The preparation method of grape seed extract tablet comprises the following steps:

[0052] (1) material preparation

[0053] For every 1000 tablets, 95g of grape seed extract, 25.5g of calcium ascorbate, 270.5g of microcrystalline cellulose 101, 165g of calcium hydrogen phosphate, 20g of povidone K30, 45g of crospovidone, 6g of silicon dioxide, stearin Magnesium acid 7g, coating powder 18g and 95% ethanol 100g;

[0054] (2) Adhesive preparation

[0055] Add 50 g of purified water in 95% ethanol to make 150 g of ethanol binder with 65% concentration;

[0056] (3) mixed

[0057] Add grape seed extract, microcrystalline cellulose 101, 82.5g of calcium hydrogen phosphate, and povidone K30 into the wet granulator, stir at low speed with the paddle of the wet granulator and cut with the cutter at low speed, mix for 4 minutes, and mix After uniformity, the mixture is obtained;

[0058] (4) soft material

[0059] The wet granulator continues to stir the mixture at a low ...

Embodiment 2

[0093] The preparation method of grape seed extract tablet comprises the following steps:

[0094] (1) material preparation

[0095] For every 1000 tablets, 100g of grape seed extract, 28.61g of calcium ascorbate, 286.79g of microcrystalline cellulose 101, 180g of calcium hydrogen phosphate, 21g of povidone K30, 50g of crospovidone, 6.8g of silicon dioxide, hard Magnesium fatty acid 6.8g, coating powder 20g and 95% ethanol 96g;

[0096] (2) Adhesive preparation

[0097] Add 44g of purified water in 95% ethanol to make 140g of ethanol binder with 65% concentration;

[0098] (3) mixed

[0099] Add grape seed extract, microcrystalline cellulose 101, 90g of calcium hydrogen phosphate, and povidone K30 into the wet granulator, stir with the paddle of the wet granulator at low speed and cut with the cutter at low speed, mix for 5 minutes, and mix well After the mixture;

[0100] (4) soft material

[0101] The wet granulator continues to stir the mixture at a low speed, adjust ...

Embodiment 3

[0131] The preparation method of grape seed extract tablet comprises the following steps:

[0132] (1) material preparation

[0133] For every 1000 tablets, 105g of grape seed extract, 29g of calcium ascorbate, 290g of microcrystalline cellulose 101, 190g of calcium hydrogen phosphate, 24g of povidone K30, 55g of crospovidone, 7g of silicon dioxide, and magnesium stearate 7g, 22g of coating powder and 96g of 95% ethanol;

[0134] (2) Adhesive preparation

[0135] Add 44g of purified water in 95% ethanol to make 140g of ethanol binder with 65% concentration;

[0136] (3) mixed

[0137] Add grape seed extract, microcrystalline cellulose 101, 95g of calcium hydrogen phosphate, and povidone K30 into the wet granulator, stir at low speed with the paddle of the wet granulator and cut with the cutter at low speed, mix for 4.5 minutes, and mix After uniformity, the mixture is obtained;

[0138] (4) soft material

[0139] The wet granulator continues to stir the mixture at a low ...

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Abstract

The invention discloses a method for preparing grape seed essence tablets, including material preparation, adhesive preparation, mixing, soft material preparation, drying, QA intermediate control, granulation, total mixing, tablet compression, QA sampling detection, coating, and drying , QA sampling testing and packaging. The grape seed essence tablets prepared by the present invention all comply with the "Pharmacopoeia of the People's Republic of China" and relevant national standards, which greatly improves the practicability, edibility and portability of grape seeds, and has great influence on the consumption of grape seeds. Innovation to promote the beneficial effects of grape seeds on the human body; in the process of producing grape seed essence tablets, the boiling granulator used for drying soft materials can improve the rapid drying of soft materials, reduce the problem of re-accumulation of soft materials, and improve the quality of grape seeds. Each ingredient in the seed essence tablet is fused with each other to improve the quality of the finished grape seed essence tablet.

Description

technical field [0001] The invention relates to the technical field of health care products, in particular to a method for preparing grape seed essence tablets. Background technique [0002] Grape seeds are rich in anthocyanins, which can scavenge free radicals, anti-aging, enhance immunity, and prevent some substances from damaging human cells. The main functions include anti-free radicals, lowering blood lipids, protecting skin and brain, anti-allergic, and anti-radiation And protect blood vessel tissue, etc., especially to protect human organs and tissues, and have a certain preventive effect on chronic diseases such as heart disease, diabetes, and arteriosclerosis. And it can protect the eyes from radiation damage, enhance night vision, reduce retinopathy, etc., and the anthocyanins in it can also protect our digestive system, gastric mucosa, and prevent our ulcers and various ulcer diseases. At present, grape seeds are usually eaten directly for digestion and absorptio...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/28A61K47/38A61K47/32A61P39/06A61P37/04A61K36/87
CPCA61K9/2027A61K9/2054A61K9/2095A61K9/28A61K36/87A61P37/04A61P39/06
Inventor 陈斌陈国靖汪善文
Owner BRAVEIY BIOTECHNOLOGY (ANHUI) CO LTD
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