Intestinal dialysis composition for pet dogs and cats and preparation method thereof

Abstract

The invention discloses a composition for intestinal dialysis of pet dogs and cats and a preparation method thereof, belonging to the pet medical field. The dialysis composition comprises the following components: 10-20g of raw rhubarb, 10-20g of chitosan, 10-20g of calcium butyrate, 50-100g of modified zeolite, and 200-300ml of acetic acid with a volume fraction of 4%. During preparation, fully dissolve raw rhubarb, chitosan and calcium butyrate in acetic acid, then add modified zeolite to make a paste, make it fully infiltrated, granulate with a granulator, and dry at 60°C for 4 hours. Finished products with a particle size of 0.8‑1.2mm. The components of the intestinal dialysis composition for pet dogs and cats provided by the present invention cooperate with each other, and can absorb uremic toxins such as urea in the intestinal tract and their decomposition products such as ammonia, phosphate, creatinine, etc., and promote blood circulation. Small molecular substances such as uremic toxins such as urea are excreted into the intestinal cavity, thereby reducing the concentration in the blood, relieving hypernitremia and hyperphosphatemia caused by renal failure, and benefiting the recovery of renal failure. Economical and easy to operate.

Description

technical field [0001] The invention belongs to the pet medical field, in particular to an intestinal dialysis composition for preventing and treating renal failure in pet dogs and cats. Background technique [0002] Studies have shown that uremic toxins such as serum urea and creatinine come from protein decomposition and intestinal absorption, and are mainly excreted through the kidneys. When kidney disease occurs, it can cause hyperureaemia. Uremic toxins such as urea and its metabolite hydrocyanate can inhibit the activity of many enzymes (monoammonium oxidase, xanthine oxidase, etc.), affect cell functions, and promote the occurrence and development of diseases, thus reducing blood urea and other uremia. Toxins hold the key to treating kidney failure in pets. The treatment of renal failure in dogs and cats mainly adopts symptomatic treatment to improve various clinical symptoms caused by excretory function, regulatory function and biosynthetic dysfunction, thereby prol...

AI Technical Summary

Problems solved by technology

However, due to the high cost and high technical requirements of hemodialysis and kidney transplantation, it is still difficult to apply in small animal clinics in my country. As an important part of renal replacement therapy, peritoneal dialysis requires costs and technical requirements The requirements are relatively low, and it is relatively easy to be accepted by animal owners. It has been used in the treatment of dogs and cats with renal failure.

[0003] At present, the peritoneal dialysis solution of dogs and cats generally uses the dialysis solution used by humans with glucose as the main osmotic agent. Due to its high sugar, hyperosmosis, low pH value and the production of glucose degradation products, it will cause changes in the structure and function of the peritoneum, and It will eventually lead to peritoneal fibrosis and peritoneal ultrafiltration failure. In addition, it can also lead to the loss of nutrients in dogs and cats, and accompanying diseases such as hypoproteinemia, hyperlipidemia, and hyperinsulinemia, which seriously affect the health of pet dogs and cats. Quality of life, increased financial burden and emotional distress for pet owners

[0004] Both hemodialysis and peritoneal dialysis achieve the purpose of reducing blood uremic toxins such as uremic toxins through the diffusion principle of uremic toxins such as urea, but there are disadvantages such as high cost, great harm to pets, and inconvenient operation.

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