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Probiotic preparation for conditioning intestinal flora imbalance of tumor patients after radiotherapy and chemotherapy and application thereof

A technology for intestinal flora imbalance and probiotic preparations, which can be used in applications, Streptococcus/Lactococcus, medical preparations containing active ingredients, etc. problems, to achieve the effect of improving activity, enhancing effect, and improving side effects

Inactive Publication Date: 2020-03-17
唐晓磊
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Existing probiotic preparations are aimed at people with high immunity, and the supplementary strains are relatively small and untargeted; the ingredients of these probiotic preparations are only probiotics, and there is a certain degree of competition among various probiotics and mutual inhibition, probiotics may become harmful bacteria for tumor patients with low immunity; only supplementing probiotics does not improve the autoimmunity of tumor patients has little effect on regulating the intestinal flora imbalance after radiotherapy and chemotherapy; the current probiotics Insufficient embedding technology, resulting in the inability of probiotics to reach the designated site and a low rate of long-lasting survival

Method used

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  • Probiotic preparation for conditioning intestinal flora imbalance of tumor patients after radiotherapy and chemotherapy and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A probiotic preparation for regulating the intestinal flora imbalance of tumor patients after radiotherapy and chemotherapy, characterized in that: the probiotic preparation includes probiotics, vitamins, trace elements, proteins, Chinese medicine extracts, sugar and auxiliary components;

[0018] The probiotics include the following components in parts by mass: 10 parts of Bifidobacterium longum, 10 parts of Bifidobacterium breve, 10 parts of Bifidobacterium bifidobacterium, 10 parts of Bifidobacterium adolescentis, 10 parts of Lactobacillus acidophilus , 10 parts of Lactobacillus fermentum, 10 parts of Lactobacillus paracasei, 10 parts of Lactobacillus plantarum, 10 parts of Lactobacillus rhamnosus, 5 parts of Streptococcus thermophilus.

[0019] The vitamins include the following components by mass fraction: VC 45mg / 100g, VE 5mg / 100g, VB 10.5mg / 100g, VB2 0.6mg / 100g, VB6 0.3mg / 100g, VB12 2μg / 100g, Vk 30μg / 100g , Folic acid 35μg / 100g.

[0020] The trace elements inclu...

Embodiment 2

[0026] A probiotic preparation for regulating the intestinal flora imbalance of tumor patients after radiotherapy and chemotherapy, characterized in that: the probiotic preparation includes probiotics, vitamins, trace elements, proteins, Chinese medicine extracts, sugar and auxiliary components;

[0027] The probiotics include the following components in parts by mass: 18 parts of Bifidobacterium longum, 13 parts of Bifidobacterium breve, 23 parts of Bifidobacterium bifidobacterium, 18 parts of Bifidobacterium adolescentis, 18 parts of Lactobacillus acidophilus , 23 parts of Lactobacillus fermentum, 15 parts of Lactobacillus paracasei, 20 parts of Lactobacillus plantarum, 13 parts of Lactobacillus rhamnosus, 8 parts of Streptococcus thermophilus.

[0028] The vitamins include the following components by mass fraction: VC 45mg / 100g, VE 5mg / 100g, VB 10.5mg / 100g, VB2 0.6mg / 100g, VB6 0.3mg / 100g, VB12 2μg / 100g, Vk 30μg / 100g , Folic acid 35μg / 100g.

[0029] The trace elements inclu...

Embodiment 3

[0035] A probiotic preparation for regulating the intestinal flora imbalance of tumor patients after radiotherapy and chemotherapy, characterized in that: the probiotic preparation includes probiotics, vitamins, trace elements, proteins, Chinese medicine extracts, sugar and auxiliary components;

[0036] The probiotics include the following components in parts by mass: 25 parts of Bifidobacterium longum, 15 parts of Bifidobacterium breve, 35 parts of Bifidobacterium bifidobacterium, 25 parts of Bifidobacterium adolescentis, 25 parts of Lactobacillus acidophilus , 35 parts of Lactobacillus fermentum, 20 parts of Lactobacillus paracasei, 30 parts of Lactobacillus plantarum, 15 parts of Lactobacillus rhamnosus, 10 parts of Streptococcus thermophilus.

[0037] The vitamins include the following components by mass fraction: VC 45mg / 100g, VE 5mg / 100g, VB 10.5mg / 100g, VB2 0.6mg / 100g, VB6 0.3mg / 100g, VB12 2μg / 100g, Vk 30μg / 100g , Folic acid 35μg / 100g.

[0038] The trace elements incl...

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Abstract

The invention discloses a probiotic preparation for conditioning intestinal flora imbalance of tumor patients after radiotherapy and chemotherapy and an application thereof, and relates to the technical field of probiotic preparations. The probiotic preparation comprises probiotics, vitamins, trace elements, proteins, traditional Chinese medicine extract, sugar and auxiliary components. The probiotics comprise the following components in parts by mass: 10 to 25 parts of bifidobacterium longum, 10 to 15 parts of bifidobacterium breve, 10 to 35 parts of bifidobacterium bifidum, 10 to 25 parts ofbifidobacterium adolescentis, 10 to 25 parts of lactobacillus acidophilus, 10 to 35 parts of lactobacillus fermentum, 10 to 20 parts of lactobacillus paracasei, 10 to 30 parts of lactobacillus plantarum, 10 to 15 parts of lactobacillus rhamnosus and 5 to 10 parts of streptococcus thermophilus.

Description

technical field [0001] The invention relates to the technical field of probiotic preparations, in particular to a probiotic preparation for regulating intestinal flora imbalance of tumor patients after radiotherapy and chemotherapy and an application thereof. Background technique [0002] Existing probiotic preparations are aimed at people with high immunity, and the supplementary strains are relatively small and untargeted; the ingredients of these probiotic preparations are only probiotics, and there is a certain degree of competition among various probiotics and mutual inhibition, probiotics may become harmful bacteria for tumor patients with low immunity; only supplementing probiotics does not improve the autoimmunity of tumor patients has little effect on regulating the intestinal flora imbalance after radiotherapy and chemotherapy; the current probiotics Insufficient embedding technology leads to the failure of probiotics to reach the designated site and the low rate o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/747A61K36/481A23L33/105A23L33/125A23L33/135A23L33/15A23L33/16A23L33/175A23L33/19A61P1/00A61K35/744A61K35/745
CPCA61K35/745A61K35/747A61K35/744A61K36/074A61K36/481A61P1/00A23L33/135A23L33/105A23L33/15A23L33/125A23L33/19A23L33/175A23L33/16A23V2002/00A23V2400/143A23V2400/113A23V2400/175A23V2400/169A23V2400/513A23V2400/517A23V2400/249A23V2400/519A61K2300/00A23V2200/32
Inventor 唐晓磊
Owner 唐晓磊
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