Compositions, devices and methods for treating autism
一种自闭症、药物的技术,应用在药理学和微生物学,医学和胃肠学领域,能够解决细菌过度感染难检测出来等问题
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Embodiment 1
[0145] A 14-year-old autistic child (averbal) with OCD and severe abdominal pain, bloating, and constipation was started on rifaximin 500 mg bid and metronidazole 200 bid and later increased to 400 bid for gastrointestinal symptoms. His bowel symptoms gradually improved, though not completely, and vancomycin 250 mg bid was added. Over the next 6 months, his abdominal symptoms completely disappeared and he could sleep through the night without being woken up by the pain. About 9 months into his ongoing treatment, the parents reported via Skype consultation in the presence of his two caregivers that the boy is now in school, speaks more than 800 words, and follows orders. During the consultation, the child was asked to go to the garage and retrieve his father's coat, which was in the back seat of the car. The child quickly carried out the request. He continues to take oral medication and attend school.
Embodiment 2
[0147] A 22-year-old male with autism who cannot utter more than 2 words (mom and "no") was brought to treatment mainly because of his aggressive behavior (requiring two paramedics to keep him in office) and self-harming OCD. He banged his head against a brick wall until the scalp was cut so deep that the bone was visible and bled. He was scheduled to receive tinidazole 500 mg bid, rifaximin 500 mg bid 2 weeks later increasing to 1 g bid, and vancomycin 250 mg II bid. Over the next 6 months, the patient gradually lost her aggression, was able to sit and watch movies, and gradually lost most of her OCD symptoms, especially chewing on a large rubber "snake" toy. Over the next 6 months, the patient learned to say 3 words. Given the marked improvement in his behavior and language development, he continued his medication.
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