Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Flavone chromium and its producing method and use

A production method and technology of flavonoid chromium, applied in the field of flavonoid chromium and its production and application, can solve the problems such as the difficulty of inorganic chromium, achieve low cost, improve sensitivity, prevent and treat diabetes

Inactive Publication Date: 2003-05-28
宁夏百信生物科技有限公司
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Inorganic chromium is not easy to be absorbed by the human body, and the aforementioned several existing organic chromium compounds, in addition to simple chromium supplementation, can only increase some nutrients such as vitamins and proteins
Plants contain a lot of flavonoids, such as rutin, licorice flavonoids, etc. As a drug, it has pharmacological functions such as softening and dilating blood vessels, normalizing microcirculation, lowering blood fat, protecting liver, and anti-oxidation. The function of chromium to improve sugar metabolism

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The flavonoid chromium is a complex formed by flavonoids and trivalent chromium, and its general molecular formula is RCrOH, wherein R is a large class of natural compounds containing the following general structural formula:

[0029] This flavonoid compound is rutin, and the flavonoid chromium molecular formula that it forms with trivalent chromium is: (C 27 o 16 h 31 )CrOH, the reaction equation is:

[0030]

[0031] The production method of this flavonoid chromium is made up of following specific steps:

[0032] (1) Rutin and methanol are dropped into the reactor in a ratio of 1:40 (w / v);

[0033] (2) Add chromium trichloride according to the molar ratio of rutin to chromium 1:1, heat to dissolve, heat and react at 60-80°C, and slowly add methanol ammonia dropwise, the color of the solution is from green to yellow -The order of brown changes, when the pH of the solution is 6, the color is dark brown, reflux reaction for 0.5 hours, when continuing to drop...

Embodiment 2

[0036] The flavonoid chromium is a complex formed by flavonoids and trivalent chromium in licorice, and its general molecular formula is RCrOH, wherein R is a licorice flavonoid containing the following general structure:

[0037] The production method of this flavonoid chromium is made up of following specific steps:

[0038] (1) Put licorice flavonoids and methanol into the reactor in a ratio of 1:40 (w / v);

[0039] (2) Add chromium trichloride according to the molar ratio of licorice flavonoids and chromium 1:1, heat to dissolve, heat and react at 60-80°C, and slowly add methanol ammonia dropwise, the color of the solution is from green to yellow -The order of brown changes, when the pH of the solution is 6, the color is dark brown, reflux reaction for 0.5 hours, when continuing to drop methanol ammonia, a large amount of precipitation will be formed, until the pH of the solution is 7.5, the precipitation is complete, the precipitation It is flavonoid chromium, named as ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Flavone compound and chromium compound are made to react to produce flavone chromium. Flavone chromium, unlike inorganic chromium compound being not easy to be absorbed by human body, has the comprehensive curative effect of both flavone and chromium compound and can promote and raise the sensitivity of insulin, soften and dilate blood vessel, improve microcirculation, regulate metabolism, prevent and cure diabetes, hyperlipomia, hypertension, and other diseases.

Description

technical field [0001] The invention relates to a flavonoid chromium and its production method and application. Background technique [0002] Chromium is an essential trace element for the human body. The organic compounds of chromium that can be seen include chromium gluconate, yeast chromium, chromium sodium chlorophyllinate and chromium picolinate. Trivalent chromium forms glucose tolerance factor in the body and promotes glucose metabolism. Chromium deficiency in the human body can disturb glucose metabolism, leading to abnormal glucose tolerance and diabetes. Inorganic chromium is not easily absorbed by the human body, and the aforementioned several existing organic chromium compounds can only increase nutrients such as vitamins and proteins in addition to simple chromium supplementation. Plants contain a lot of flavonoids, such as rutin, licorice flavonoids, etc. As a drug, it has pharmacological functions such as softening and dilating blood vessels, normalizing mic...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/352A61P3/00A61P3/06A61P3/10A61P9/10C07D311/28
Inventor 刘钢刘祎春李学强熊楚明
Owner 宁夏百信生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com