Biological enrichment factor prediction method for formulating water quality standard and risk assessment
A bioaccumulation and prediction method technology, applied in the fields of genomics, biostatistics, bioinformatics, etc., can solve the constraints on the development of chemical safety management and environmental risk management, the lack of data on bioaccumulation factors, and the inability to meet the needs of species Diversity requirements and other issues to achieve the effect of avoiding biological experiments, meeting the needs of biodiversity, and avoiding time-consuming and labor-intensive effects
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[0041](1) Taking the black-headed minnow as the predicted species and the guppy as the substitute species, through literature research and database search, the same enriched organs, developmental stages, experimental methods, experimental conditions, exposure routes and purity of chemicals were screened out. Bioconcentration factors of grades of minnow and guppy. The geometric mean value of all bioconcentration factors corresponding to the same chemical in the same species was taken, and the bioconcentration factor data of 12 chemicals with different structures were matched after the same compound of the two species was matched, as shown in Table 1.
[0042] Table 1: BCF data of the BCF-ICE model based on guppy and blackhead minnow, unit (L / kg)
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[0044]
[0045] (2) Based on the bioaccumulation factor data of 12 different structural chemicals, the BCF-ICE model between two species was established, and the BCF-ICE model was established as attached figure 1 shown...
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