Prostate bacteriostatic gel and preparation method thereof

A technology of prostate and gel, applied in the field of medicine, can solve the problems of hindering the passage of water-soluble antibiotics, and the effect is not ideal.

Inactive Publication Date: 2020-04-17
赵显梁
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the drugs for treating prostatitis are generally administered orally or by injection, but there is a prostate-blood barrier composed of lipid membrane between the prostate acini and the microcirculation, which hinders the passage of water-soluble antibiotics through the barrier, and the effect is not ideal.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Prostate antibacterial gel, its preparation method is as follows:

[0050] 1) Weigh Phellodendron 30g, Smilax 20g, Angelica 10g, Purslane 20g, Eupatorium 20g, Sophora flavescens 10g, Dandelion 10g, Scutellaria baicalensis 8g, Safflower 6g, Coptidis 5g, Lonicera vine 5g, Plantago 4g, Longan 3g of bile grass, 3g of wild chrysanthemum, 10g of biopeptide and 8g of vitamin E are used as spare materials, and cellulose, purified water, glycerin and propylene glycol are used as auxiliary materials for later use;

[0051] 2) Mix Phellodendron, Smilax, Angelica, Purslane, Eupatorium, Sophora, Dandelion, Scutellaria, Safflower, Coptidis, Lonicera, Plantain, Gentian and Wild Chrysanthemum, crush and grind, pass through 40 mesh Sieve to obtain mixed powder for subsequent use;

[0052] 3) Add ethanol with 5 times the mass of the mixed powder to the mixed powder, heat and reflux at 80°C for 5h, and concentrate under reduced pressure at 25kPa at 60°C to 0.2 times the original volume, ...

Embodiment 2

[0055] Prostate antibacterial gel, its preparation method is as follows:

[0056] 1) Weigh 30g Cortex Phellodendri, 10g Smilax, Angelica 10g, Purslane 20g, Eupatorium 20g, Sophora flavescens 10g, Dandelion 10g, Scutellaria baicalensis 5g, Safflower 3g, Coptidis 1g, Lonicera vine 1g, Plantago 2g, Longan 1g of bile grass, 1g of wild chrysanthemum, 5g of biopeptide and 5g of vitamin E are used for standby, and carbomer, purified water, glycerin and propylene glycol are used as auxiliary materials for standby;

[0057] 2) Mix Phellodendron, Smilax, Angelica, Purslane, Eupatorium, Sophora, Dandelion, Scutellaria, Safflower, Coptidis, Honeysuckle, Plantago, Gentian and Wild Chrysanthemum, crush and grind, pass through 20 mesh Sieve to obtain mixed powder for subsequent use;

[0058] 3) Add 90% ethanol of 3 times the mass of the mixed powder to the mixed powder, heat and reflux at 60°C for 4h, concentrate under reduced pressure at 40°C to 0.2 times the original volume at 40°C, crush...

Embodiment 3

[0061] Prostate antibacterial gel, its preparation method is as follows:

[0062] 1) Weigh 50g Cortex Phellodendri, 50g Smilax, Angelica 40g, Purslane 30g, Eupatorium 30g, Sophora flavescens 20g, Dandelion 20g, Scutellaria baicalensis 10g, Safflower 6g, Coptidis 10g, Lonicera vine 10g, Plantago 10g, Longan 5g of bile grass, 5g of wild chrysanthemum, 20g of biopeptide and 10g of vitamin E are used as spare materials, and carbomer, cellulose, purified water, glycerin and propylene glycol are used as auxiliary materials for use;

[0063] 2) Mix Phellodendron, Smilax, Angelica, Purslane, Eupatorium, Sophora, Dandelion, Scutellaria, Safflower, Coptidis, Lonicera, Plantain, Gentian and Wild Chrysanthemum, crush and grind, pass through 40 mesh Sieve to obtain mixed powder for subsequent use;

[0064] 3) Add ethanol with 5 times the mass of the mixed powder to the mixed powder, heat and reflux at 80°C for 6h, 35kPa, and concentrate under reduced pressure at 60°C to 0.2 times the orig...

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PUM

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Abstract

The invention, which belongs to the medicine field, discloses prostate bacteriostatic gel and a preparation method thereof. The prostate bacteriostatic gel comprises active components and auxiliary materials in a mass ratio of (1-2): 4. The active component comprises the following raw materials: corktree bark, rhizoma smilacis glabrae, Chinese angelica, herba portulacae, herba lycopi, lightyellowsophora root, dandelion, the root of large-flowered skullcap, red flower, the rhizome of Chinese goldthread, honeysuckle stem, plantain seed, Japanese gentian root, flos chrysanthemi indici, biological peptide and vitamin E. The prostate bacteriostatic gel disclosed by the invention has the beneficial effects: efficient antibacterial and anti-inflammatory effects are realized and the harmful florais killed; the gel has no drug resistance and is mild and has no irritation; local analgesia is realized; the pain is eliminated or reduced after conditioning; the local immune function is adjusted and improved; the humoral immunity inhibiting effect is realized; with the unique traditional Chinese medicine ingredients, direction permeation and enveloping are performed directly and the medicine absorption is facilitated; the medicine reaches the affected part directly; the prostate local antibacterial factor activity is enhanced; chronic congestion is improved; gland tissue proliferation is inhibited; gland duct obstruction is relieved; gland fluid drainage is promoted, and the like.

Description

technical field [0001] The invention relates to a gel and a preparation method thereof, in particular to a prostate antibacterial gel and a preparation method thereof, belonging to the field of medicine. Background technique [0002] The prostate (prostate) is a male-specific gonad organ, which is composed of glandular tissue and muscle tissue. It is a very rare sex secretory gland with both internal and external secretion functions in the human body. As an exocrine gland, the prostate secretes about 2 ml of prostatic fluid every day , is the main component of semen; as an endocrine gland, the hormone secreted by the prostate is called "prostaglandin". [0003] Prostatitis (prostatitis) is a common disease in urology. It refers to a prostate disease caused by a variety of complicated reasons, with urethral irritation and chronic pelvic pain as the main clinical manifestations. It can be roughly divided into specific prostatitis and non-specific prostatitis. , specific prost...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/90A61K36/896A61K38/02A61K9/06A61K47/32A61K47/38A61P13/08A61P15/00A61P15/08A61P13/00A61P13/10A61P31/04A61P31/10A61K31/355
CPCA61K9/0031A61K9/06A61K31/355A61K36/185A61K36/232A61K36/286A61K36/287A61K36/288A61K36/355A61K36/489A61K36/515A61K36/53A61K36/539A61K36/68A61K36/718A61K36/756A61K36/896A61K36/90A61K38/02A61K47/32A61K47/38A61P13/00A61P13/08A61P13/10A61P15/00A61P15/08A61P31/04A61P31/10A61K2300/00
Inventor 赵显梁
Owner 赵显梁
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