Immune adjustment preparation for treating chronic periodontitis and preparation method of immune adjustment preparation for treating chronic periodontitis

A technology for chronic periodontitis and immune regulation, applied in the field of periodontitis treatment drugs, can solve the problem that the body is easily affected by other viruses, and achieve the effects of enhancing the body's immune function, relieving tooth swelling and pain, and promoting recovery.

Inactive Publication Date: 2020-05-12
AFFILIATED STOMATOLOGICAL HOSPITAL OF NANJING MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide an immunomodulatory preparation for treating chronic periodontitis and a preparation method thereof, so as to solve the problem that the existing immunomodulatory preparations for chronic periodontitis proposed in the above-me

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] An immunomodulatory preparation for treating chronic periodontitis, comprising the following components in parts by weight:

[0033] 4 parts rhubarb;

[0034] 7 parts of Scutellaria baicalensis;

[0035] Forsythia 10 parts;

[0036] Houttuynia cordata 7 parts;

[0037] 8 parts honeysuckle;

[0038] 11 parts soap thorn;

[0039] Diding 12 parts;

[0040] 9 parts of licorice;

[0041] The preparation method of the above immunomodulatory preparation for the treatment of chronic periodontitis is as follows: the raw materials rhubarb, baicalin, forsythia, houttuynia cordata, honeysuckle, saponins, diding and licorice are respectively pulverized into fine powder, and mixed according to the above weight parts. Evenly, add 70% ethanol with an alcohol concentration of 3 to 5 times the mass of the mixture, heat and reflux for extraction 1 to 3 times, each time for 1 to 2 hours, combine the extracts, filter, and recover ethanol from the filtrate under reduced pressure, conce...

Embodiment 2

[0043] An immunomodulatory preparation for treating chronic periodontitis, comprising the following components in parts by weight:

[0044] 6 parts rhubarb;

[0045] 12 parts of Scutellaria baicalensis;

[0046] Forsythia 12 parts;

[0047] Houttuynia cordata 6 parts;

[0048] 14 parts honeysuckle;

[0049] 6 parts soap thorn;

[0050] Diding 8 parts;

[0051] 5 parts licorice;

[0052] 4 parts mint;

[0053] The preparation method of the above-mentioned immunomodulatory preparation for the treatment of chronic periodontitis is as follows: the raw materials rhubarb, baicalin, forsythia, houttuynia cordata, honeysuckle, saponins, diding, licorice and peppermint are respectively pulverized into fine powder, and the above-mentioned weight Mix the parts evenly, add 70% ethanol with an alcohol concentration of 3 to 5 times the mass of the mixture, heat and reflux for extraction 1 to 3 times, each time for 1 to 2 hours, combine the extracts, filter, recover the ethanol from t...

Embodiment 3

[0055] An immunomodulatory preparation for treating chronic periodontitis, comprising the following components in parts by weight:

[0056] 10 parts rhubarb;

[0057] 8 parts of Scutellaria baicalensis;

[0058] Forsythia 16 parts;

[0059] Houttuynia cordata 8 parts;

[0060] 10 parts honeysuckle;

[0061] 7 parts soap thorn;

[0062] Diding 6 parts;

[0063] 5-10 parts of licorice;

[0064] 7 parts yam;

[0065] The preparation method of the above-mentioned immunomodulatory preparation for the treatment of chronic periodontitis is as follows: the raw materials rhubarb, baicalin, forsythia, houttuynia cordata, honeysuckle, saponins, ditin, licorice and Chinese yam are respectively pulverized into fine powder, and the above-mentioned weight Mix the parts evenly, add 70% ethanol with an alcohol concentration of 3 to 5 times the mass of the mixture, heat and reflux for extraction 1 to 3 times, each time for 1 to 2 hours, combine the extracts, filter, recover the ethanol f...

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PUM

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Abstract

The invention discloses an immune adjustment preparation for treating chronic periodontitis and a preparation method of the immune adjustment preparation for treating chronic periodontitis, and belongs to the technical field of periodontitis treatment medicines. The preparation comprises the following components in parts by weight of 4-10 parts of radix et rhizoma rhei, 6-12 parts of radix scutellariae, 10-16 parts of fructus forsythiae, 6-12 parts of heartleaf houttuynia herbs, 5-14 parts of honeysuckle flowers, 5-11 parts of spina gleditsiae, 6-12 parts of herba violae and 5-10 parts of licorice roots. The preparation method comprises the following steps of respectively crushing raw materials to obtain fine powder, performing uniform mixing in parts by weight, adding ethanol, performingheating and reflux extraction for 1-3 times, combining extracting solutions, performing filtration, performing concentration, removing ethanol, obtaining paste, performing crushing to obtain powder, and performing screening with a 20-mesh sieve so as to obtain the immune adjustment preparation. According to the immune adjustment preparation disclosed by the invention, the heartleaf houttuynia herbs, the honeysuckle flowers and the fructus forsythiae have the efficacy of resisting bacteria, so that the capacity of a product medicine for restraining pathogenic bacteria can be increased, and thepossibility that organisms are easily influenced by other viruses due to reduction of immunity of the organisms at the period of tooth inflammation can be reduced; and besides, the heartleaf houttuynia herbs also have the treatment effect of reinforcing the immune functions of the organisms, so that the swallowing capacity of leucocyte can be increased, and the treatment effects of the product medicine can be increased.

Description

technical field [0001] The invention relates to the technical field of medicines for treating periodontitis, in particular to an immunomodulatory preparation for treating chronic periodontitis and a preparation method thereof. Background technique [0002] Periodontitis is a chronic inflammatory and destructive disease that invades the gums and periodontal supporting tissues; its main features are: periodontal pocket formation, gingival inflammation, alveolar bone resorption and tooth loosening; with the continuous development of science and technology , medical technology is also constantly maturing, so that the innovation and design of drugs for periodontitis treatment play a role in promoting the development of medical technology. [0003] Because the existing immunomodulatory preparations for the treatment of chronic periodontitis can not reduce inflammation and also have the effect of anti-inflammation and improving the immune function of the body, the patient is vulner...

Claims

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Application Information

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IPC IPC(8): A61K36/86A61K36/8945A61P1/02A61P37/04
CPCA61K36/355A61K36/483A61K36/484A61K36/534A61K36/539A61K36/634A61K36/708A61K36/78A61K36/815A61K36/86A61K36/8945A61K2236/333A61K2236/39A61K2236/51A61P1/02A61P37/04A61K2300/00
Inventor 孙雯王华杨秋冬
Owner AFFILIATED STOMATOLOGICAL HOSPITAL OF NANJING MEDICAL UNIV
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