Traditional Chinese medicine composition and application thereof, and medicine containing traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition. The traditional Chinese medicine composition is composed of berberine and astragaloside. Meanwhile, the invention provides an application of the traditional Chinese medicine composition in preparation of a medicine used for treating type-2 diabetes mellitus by regulating intestinal flora. The traditional Chinese medicine composition provided by the invention has the following advantages: only when the berberine and the astragaloside are used in combination, the change of specific flora in the intestinal flora is related to hypoglycemic activity, so blood glucose is reduced; meanwhile, the traditional Chinese medicine composition has the beneficial effects of repairing intestinal barrier damage and / or adjusting the change of an intestinal flora structure (relative abundance), etc.

Description

technical field [0001] The invention belongs to the technical field of medicines, and specifically relates to a traditional Chinese medicine composition, its use, and medicines containing the traditional Chinese medicine composition. Background technique [0002] At present, China has become the country with the largest number of diabetic patients in the world, and nearly 90% of diabetics are diagnosed as type 2 diabetes. Type 2 diabetes is one of the chronic metabolic diseases threatening human health worldwide. Therefore, it is urgent to accelerate the development of safe and effective new drug research for the prevention of type 2 diabetes. Type 2 diabetes is a chronic metabolic disease and belongs to the category of dominant diseases in traditional Chinese medicine. Traditional Chinese medicine has a definite clinical effect on this disease. [0003] Coptis chinensis and Astragalus membranaceus appear frequently in the classic prescriptions of traditional Chinese medic...

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Problems solved by technology

[0004] In order to solve the problem that the mechanism of traditional Chinese medicine for treating diabetes cannot be clearly understood in the prior art, which hinders the development of Chinese medicine for treating diabetes, the invention discloses a traditional Chinese medicine composition, its preparation method and use, and a Chinese medicine composition containing the same. The purpose is to explore the mechanism of action of traditional Chinese medicine in treating diabetes, especially for type 2 diabetes, to provide solid basic theoretical support for enriching the ingredients of traditional Chinese medicine in the treatment of diabetes, and to promote the development of traditional Chinese medicine

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